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Epitope Incorporated Company Profile

19:00 EDT 21st September 2017 | BioPortfolio

Epitope, Inc. develops and markets oral specimen collection kits and related diagnostic tests primarily for the detection of the Human Immunodeficiency Virus (HIV), the cause of Acquired Immune Deficiency Syndrome (AIDS), and for the detection of other medical conditions and analytes, including drugs of abuse. Epitope's lead product, the patented OraSure(R) collection device, is used as part of an oral specimen diagnostic system. The Company markets the device in the United States and certain foreign countries for use in screening life insurance applicants and for public health use, and plans to begin marketing for drugs of abuse testing in 1999.

Location

8505 S.W. Creekside Place
Beaverton
OR
97008
United States of America

Contact

Phone: 503 641 6115
Fax: 503 643 2781


News Articles [14 Associated News Articles listed on BioPortfolio]

Quantifiable predictive features define epitope-specific T cell receptor repertoires

T cells are defined by a heterodimeric surface receptor, the T cell receptor (TCR), that mediates recognition of pathogen-associated epitopes through interactions with peptide and major histocompatibi...

Epitope-based blood test may identify active systemic sclerosis

MADRID — A conformational epitope-based assay may be effective in identifying systemic sclerosis patients whose disease is active, regardless of whether their condition is classified as limited or d...

Multi-epitope vaccines: a promising strategy against tumors and viral infections

Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation

Identification of a Tetanus Toxin Specific Epitope in Single Amino Acid Resolution

Vaccinations are among the most potent tools to fight infectious diseases. However, cross‐reactions are an ongoing problem and there is an urgent need to fully understand the mechanisms of the immun...

Simultaneous epitope and transcriptome measurement in single cells

Using established high-throughput single-cell RNA-seq platforms, CITE-seq combines highly multiplexed, antibody-based protein marker quantification with unbiased transcriptome profiling for thousands ...

DBV Technologies enrols first patient in Phase III peanut allergy trial

French biopharmaceutical firm DBV Technologies has started patient enrolment in a Phase III EPITOPE clinical trial of Viaskin Peanut to treat peanut allergy in young children.

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

T cells directed against mutant neo-epitopes drive cancer immunity. However, spontaneous immune recognition of mutations is inefficient. We recently introduced the concept of individualized mutanome v...

PubMed Articles [152 Associated PubMed Articles listed on BioPortfolio]

Identification of one B-cell epitope from NS1 protein of duck Tembusu virus with monoclonal antibodies.

This study describes the identification of one linear B-cell epitope on TMUV NS1 protein with monoclonal antibody (mAb) 3G2 by indirect enzyme-linked immunosorbent assay (ELISA). In this study, NS1 pr...

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope.

The identification of an antigenic epitope by the immune system allows for the understanding of the protective mechanism of neutralizing antibodies that may facilitate the development of vaccines and ...

Identification of a conserved conformational epitope in the VP2 protein of foot-and-mouth disease virus.

Foot-and-mouth disease (FMD), caused by foot-and-mouth disease virus (FMDV), is a highly contagious infectious disease that affects domestic and wild cloven-hoofed animals worldwide. VP2 is a structur...

Epitope Mapping of the Antibody Response Against the Envelope Proteins of the Feline Foamy Virus.

Foamy viruses (FV) are retroviruses that infect several species without pathological signs, but induce substantial antibody responses in the infected host. In the case of feline FV (FFV), antibodies a...

Epitope mapping of a new anti-Tn antibody detecting gastric cancer cells.

Here we introduce a novel scFv antibody, G2-D11, specific for two adjacent Tn-antigens (GalNAc -Ser/Thr) binding equally to three dimeric forms of the epitope, Ser-Thr, Thr-Thr and Thr-Ser. Compared t...

Clinical Trials [37 Associated Clinical Trials listed on BioPortfolio]

DC1s-CTL Cellular Therapy for Renal Cell Carcinoma

This trial is to evaluate the safety and effectiveness of autologous type-1 polarized dendritic cell vaccines (patients' autologous DC1s loaded with multiple antigens CTL epitope peptide c...

Safety Study of Cancer Specific Epitope Peptides Cocktail and Cyclophosphamide for Advanced or Relapsed Solid Tumors Including Cervical, Gastrointestinal (GI), and Lung Tumors

The purpose of this study is to evaluate the clinical safety and efficacies of cyclophosphamide combined cancer specific epitope peptides cocktail for advanced/relapsed solid tumors includ...

Injection Of AJCC Stage IIB, IIC, III And IV Melanoma Patients With A Multi-Epitope Peptide Vaccine Using GM-CSF DNA As An Adjuvant: A Pilot Trial To Assess Safety And Immunity

This is a pilot trial to investigate the use of GM-CSF DNA as an adjuvant for peptide vaccination in patients with metastatic melanoma. The objective of this study is to determine the safe...

A Phase I Study of gp100 Human Melanoma Peptide Vaccine With Incomplete Freund's Adjuvant

This is a phase I study of melanoma tumor antigen peptide vaccines. The nine amino acid peptides representing HLA-A2 restricted T cell epitope of the melanoma antigen, gp100 will be admin...

Histocompatibility Leukocyte Antigen (HLA)-A*2402 Restricted Peptide Vaccine Therapy in Patients With Esophageal Cancer

The purpose of this study is to evaluate the safety and time to progression of HLA-A*2402 restricted epitope peptides URLC10, TTK, and KOC1, emulsified with Montanide ISA 51.

Companies [58 Associated Companies listed on BioPortfolio]

ePitope Informatics Limited

ePitope Informatics is an Internet-based applied bioinformatics company providing services for the prediction and analysis of protein epitopes. ePitope are working in areas that include diagostics, th...

ePitope Informatics Ltd

ePitope Informatics is an Internet-based applied bioinformatics company of scientists providing a range of protein analysis and annotation services. A particular focus is epitope prediction for the id...

Epitope Incorporated

Epitope, Inc. develops and markets oral specimen collection kits and related diagnostic tests primarily for the detection of the Human Immunodeficiency Virus (HIV), the cause of Acquired Immune De...

Epitope Diagnostics, Inc.

Epitope Diagnostics will launch its innovative fecal sample-based rapid immunoassy test platform during the AACC meeting. This novel fecal sample test system is so user-friendly that it protects both ...

PRAECIS PHARMACEUTICALS INCORPORATED

PRAECIS PHARMACEUTICALS INCORPORATED is a biopharmaceutical company focused on the discovery and development of novel compounds to address unmet medical needs or improve existing therapies.PRAECIS has...

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Human Immuno Deficiency Virus (HIV)
Human Immunodeficiency Virus (HIV), the causative agent of AIDS. The Human Immunodeficiency Virus, more commonly known as HIV, is a member of the lentivirus sub-set of the retrovirus family of pathogens. It causes AIDS, or Acquired Immuno Deficiency Sy...

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