Xencor, Inc. Company Profile
Xencor, Inc. engineers superior biotherapeutics using its proprietary Protein Design Automation® technology platform, and is a leader in the field of antibody engineering to significantly improve antibody half-life, immune-regulatory function and potency. The company is advancing multiple XmAb® antibody drug candidates into the clinic, including XmAb®5871 targeting CD32b and CD19 for autoimmune diseases, an anti-CD30 candidate XmAb®2513 which recently completed a Phase 1 clinical trial for the treatment of Hodgkin’s lymphoma, and a portfolio of biosuperior antibodies that are versions of blockbuster antibody drugs engineered for superior half-life and dosing schedule. Xencor’s antibody engineering technology has been licensed through multiple partnerships with industry leaders such as Pfizer, CSL Ltd., Boehringer Ingelheim, MedImmune, Centocor and Human Genome Sciences. In these partnerships Xencor is applying its suite of proprietary antibody Fc domains to improve antibody drug candidates for traits such as sustained half-life and potency. For more information, please visit www.xencor.com.
News Articles
Monrovia, California-based Xencor licensed its Xtend technology for extending the half-life of protein therapeutics to CSL Limited for use in the development of monoclonal antibodies against an undis...
Janssen uses Xencor's technology in antibody drug development
Janssen R&D exercised an option to utilize Xencor's Xtend half-life extension technology in a therapeutic antibody as part of -More-
Xencor has received a milestone payment from  Janssen Research & Development resulting from the exercised option for the use of  Xencor’s Xtend half-life extension technology in a therapeu...
Janssen uses Xencor Xtend half-life extension technology in therapeutic antibody
Janssen Research & Development has exercised an option to use Xencor's Xtend half-life extension technology in an undisclosed therapeutic antibody, under the terms of the technology licensing deal sig...
MorphoSys AG: MorphoSys and Xencor Report Clinical Data for MOR208/XmAb5574
MorphoSys AG / MorphoSys and Xencor Report Clinical Data for MOR208/XmAb5574 . Processed and transmitted by Thomson Reuters ONE. The issuer is solely responsible for the content of this announcemen...
MorphoSys AG: MorphoSys und Xencor präsentieren klinische Daten zu MOR208/XmAb5574
MorphoSys AG / MorphoSys und Xencor präsentieren klinische Daten zu MOR208/XmAb5574 . Verarbeitet und übermittelt durch Thomson Reuters ONE. Für den Inhalt der Mitteilung ist der Emittent verantwor...
Xencor Receives Milestone Payment for Xtend™ Antibody
MONROVIA, Calif., Jan. 17, 2013 /PRNewswire/ -- Xencor, Inc. today announced it has received a milestone payment from Janssen Research & Development, LLC (Janssen R&D) resulting fro...
Drugs and Medications
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PubMed Articles
Mast cells and basophils play a central role in allergy, asthma, and anaphylaxis, as well as in non-allergic inflammatory, neurological and autoimmune diseases. Allergen-mediated cross-linking of IgE...
Clinical Trials
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Companies
Xencor™ is a biotechnology company that is commercializing Protein Design Automation™ (PDA), a proprietary research platform for protein design. PDA builds on recent groundbreaking advances in co...
Xencor, Inc. engineers superior biotherapeutics using its proprietary Protein Design Automation® technology platform, and is a leader in the field of antibody engineering to si...
Since 1997, Xencor has built the most powerful protein engineering technology platform in the biotechnology industry. Its versatility is evidenced by our success in developing two classes of superior...
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