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Inflammation

on the skin, showing the redness and swelling characteristic of inflammation . Black rings of necrotic tissue surround central areas of pusInflammation is the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. Inflammation is not a synonym for infection. Even in cases where inflammation is caused by infection it is incorrect to use the terms as synonyms: infection is caused by an exogenous pathogen, while inflammation is the response of the organism to the pathogen.In the absence of inflammation, wounds and infections would never heal and progressive destruction of the tissue would compromise the survival of the organism. However, inflammation which runs unchecked can also lead to a host of diseases, such as hay fever, atherosclerosis, and rheumatoid arthritis. It is for this reason that inflammation is normally tightly regulated by the body. Inflammation can be classified as either acute or chronic. Acute inflammation is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes from the blood into the injured tissues. A cascade of biochemical events propagates and matures the inflammatory response, involving the local vascular system, the immune system, and various cells within the injured tissue. Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells which are present at the site of inflammation and is characterised by simultaneous destruction and healing of the tissue from the inflammatory process. (From the Wikpedia article Inflammation.)

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Recent Publications on Inflammation:

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Experimental evidence of obesity as a risk factor for severe acute pancreatitis.
The incidence of acute pancreatitis, an inflammation of the pancreas, is...
13th November, 2009
Service of Gastroenterology, Geneva University Hospitals, Geneva 1205, World J Gastroenterol. 2009 Nov 14;15(42):5260-5.
Potential role of chitinase 3-like-1 in inflammation-associated carcinogenic changes of epithelial cells.
The family of mammalian chitinases includes members both with and without...
13th November, 2009
Gastrointestinal Unit, Department of Medicine, Massachusetts General World J Gastroenterol. 2009 Nov 14;15(42):5249-59.
Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease.
Neural injury leads to inflammation and activation of microglia that in...
13th November, 2009
Centro de Investigacion en Red sobre Enfermedades Neurodegenerativas Glia. 2009 Nov 11.
DOI Direct Link
Clinico-pathological and protein characterization of BRAF and K-RAS mutated colorectal cancer and implications for prognosis.
Recent evidence highlights the potential prognostic and predictive value...
13th November, 2009
Institute for Pathology, University Hospital of Basel, Basel, Switzerland. Int J Cancer. 2009 Nov 11.
DOI Direct Link
CX3CL1 (fractalkine): A signpost for biliary inflammation in primary biliary cirrhosis.
Improvements in the treatment of primary biliary cirrhosis (PBC) may...
13th November, 2009
Department of Medicine and Biosystemic Science, Kyushu University Graduate Hepatology. 2009 Nov 11.
DOI Direct Link

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Press Releases About Inflammation:

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Largest Gene Study of Childhood IBD Finds 5 New Genes 16th November, 2009 The Children's Hospital of Philadelphia
--Findings Linked to a Key Molecule Active in GI Inflammation-- PHILADELPHIA, Nov. 16 /PRNewswire-USNewswire/ -- In the largest, most comprehensive genetic analysis of childhood-onset inflammatory
Reportlinker Adds Autoimmune and Inflammation Inflammation 12th November, 2009 Reportlinker
-- Maintain a critical competitive advantage. % of Products by Phase of Development No. of Products by Phase of Development Marketed Products vs. Pipeline Products Company Overview - Pipeline
Miami-Based Family Practice Physician Hosting the Grand Opening of the Youthful Aging Center - Discover Your True Fountain of Youth! 28th October, 2009 Youthful Aging Center
MIAMI, Oct. 28 /PRNewswire/ -- After more than 17 years and over 5,000 patients seen under the traditional medical modalities, Dr. Ana M. Hernandez, DO, has broken out of the mold and is committed to
NIH Director Francis Collins to Address 3,000 Cystic Fibrosis Experts at International Conference in Minneapolis 8th October, 2009 Cystic Fibrosis Foundation
-- Coping with barriers to health care coverage for people with CF Cystic fibrosis affects about 30,000 children and adults in the United States and causes life-threatening lung infections and
Reportlinker Adds Drug Delivery Partnering Agreements in Pharma and Biotech 6th October, 2009 Reportlinker
NEW YORK, Oct. 6 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue. Reportlinker Adds Drug Delivery Partnering Agreements in Pharma and

BioNews Results for Inflammation:

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New market research report on inflammation drugs
News-Medical.Net:  Nov 13 2009 2:29PM Matching: inflammation
The Histamine H4 Receptor Mediates Inflammation and Pruritus in Th2-Dependent Dermal Inflammation
MDLinx:  Nov 13 2009 11:04AM Matching: inflammation
Acute Decline in Renal Function, Inflammation, and Cardiovascular Risk after an Acute Coronary Syndrome
MDLinx:  Nov 13 2009 11:52AM Matching: inflammation
Reportlinker Adds Autoimmune and Inflammation Inflammation
Montana's News Station:  Nov 12 2009 7:30PM Matching: inflammation
Reportlinker Adds Autoimmune and Inflammation Inflammation
KSLA:  Nov 12 2009 8:41PM Matching: inflammation
Promote your company here: BioNewsCast - Press Release Distribution

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Inflammation Clinical Trials:

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Detection of Plaque Inflammation by Positron Emission Tomography (PET)-Effects of Simvastatin on Plaque Inflammation

Inflammation Patents:

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US Patent No.Title
7615211 CD70 inhibition for the treatment and prevention of inflammatory bowel disease
7615379 Nucleic acid and corresponding protein entitled 193P1E1B useful in treatment and detection of cancer
7615380 Methods for modulating an immune response by modulating KRC activity
7615505 Inorganic fiber and method for manufacturing the same
7615532 Insulin derivatives

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Companies working in the area of Inflammation from Bioportfolio's Biocorporate database :

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A.P. Pharma

A.P. Pharma, Inc. is a specialty pharmaceutical company focused on the development and commercialization of innovative medical treatments utilizing its proprietary polymer-based drug delivery systems....
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Accredo Health

Accredo Health, Incorporated ("Accredo") is a Memphis-based parent organization for a family of companies providing specialized contract pharmacy and related services beneficial to patients with...
www.accredohealth.com/        View full profile
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Amgen Incorporated

Over the past quarter century, Amgen has pioneered the methods by which human proteins that play a role in disease processes are identified, isolated, produced in quantity and used as therapeutics....
www.amgen.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Inflammation scientists - we have details of around 16922 individuals working on Inflammation .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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