Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression

15:19 EDT 18 Mar 2013 | Nature Publishing

The authors find that serotonin, acting through 5-HT1B receptors, potentiates temporoammonic pathway–to–CA1 cell excitatory synapses in the hippocampus. Chronic unpredictable stress increased the magnitude of this potentiation, and chronic treatm...

Original Article: Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression

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