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Biomedical engineers at Duke University say they have harvested genes for ion channels from bacteria that, with a few tweaks, can create and enhance electrical signaling in human cells, making the cells more electrically excitable. The technique could one day be used to treat cardiac arrhythmia or to restore electrical functions to scarred heart or nervous system tissues, note the scientists, adding that It might also prove useful for treating a variety of genetic diseases involving poor conductivity in human sodium and calcium channels. The study ("Engineering prokaryotic channels for control of mammalian tissue excitability") appears online in Nature Communications. In mammals, the genes controlling the sodium ion channels responsible for a cell's electrical activity are surprisingly large. Too large, unfortunately, to be readily delivered to cells through a virus--standard procedure in modern gene therapy techniques. To skirt this size issue, the Duke team delivered smaller ion channels ...NEXT ARTICLE
Cardiology is a specialty of internal medicine. Cardiac electrophysiology : Study of the electrical properties and conduction diseases of the heart. Echocardiography : The use of ultrasound to study the mechanical function/physics of the h...
Cardiovascular disease (CVD)
Acute Coronary Syndromes (ACS) Blood Cardiovascular Dialysis Hypertension Stent Stroke Vascular Cardiovascular disease (CVD) includes all the diseases of the heart and circulation including coronary heart disease (angina...
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...