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Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

07:24 EST 1 Dec 2016 | News-Medical.net

Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread.

Original Article: Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

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