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Accurate identification of single-nucleotide variants in whole-genome-amplified single cells

14:43 EDT 20 Mar 2017 | Nature Publishing

Single-cell multiple displacement amplification (SCMDA) and a tool for single-nucleotide-variant calling (SCcaller) dramatically decrease artifacts in genome-wide variant calling from single cells.

Original Article: Accurate identification of single-nucleotide variants in whole-genome-amplified single cells

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Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...