Track topics on Twitter Track topics that are important to you
(Centro Nacional de Investigaciones Oncológicas (CNIO)) The initiating oncogenic event in half of human lung adenocarcinomas is still unknown, a fact that complicates the development of selective targeted therapies. Researchers at the CNIO have demonstrated that the expression of an endogenous Braf kinase-inactive isoform in mice triggers lung adenocarcinoma in vivo, indicating that BRAF-inactivating mutations are initiating events in lung oncogenesis. The paper indicates that the signal intensity of the MAPK pathway is a critical determinant in tumor development.
Original Article: A Braf kinase-inactive mutant induces lung adenocarcinomaNEXT ARTICLE
Pulmonary relating to or associated with the lungs eg Asthma, chronic bronchitis, emphysema, COPD, Cystic Fibrosis, Influenza, Lung Cancer, Pneumonia, Pulmonary Arterial Hypertension, Sleep Disorders etc Follow and track Lung Cancer News ...