Latest High-throughput Screening (HTS) News

[Articles] Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomiseREGN727 was well tolerated and achieved substantial further LDL-C reduction in patients with heterozygous familial hypercholesterolaemia and elevated LDL-C treated with high-dose statins, with or without ezetimibe. REGN727 has the potential to provid...

Diabetics May Need Early Colon Cancer Screening (CME/CE)SAN DIEGO (MedPage Today) -- Type 2 diabetes patients may need to be screened earlier for colorectal cancer, researchers said here.

Illegal immigrants find paths to college, careersGoing to college seemed inconceivable when Adriana Sanchez, the 12-year-old daughter of farm workers, was brought from Mexico to Central California and the family overstayed their visas.Even though Sanchez excelled in high school, she was in the cou...

Sanofi and Regeneron Announce Publication of Positive Phase 2 Results for Lipid-Lowering PCSK9 Antibody in The LancetPARIS and TARRYTOWN, New York, May 26, 2012 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced additional positive results from a Phase 2 trial of SAR236553/REGN727 (Study 1003, NTC01266876) in patients with heterozygous familial hypercholesterolemia (heFH). SAR236553/REGN727 is a subcutaneously administered, fully-human antibod...

News digest – clinical trials, bowel cancer screening, coffee and cancer, and moreSunday was International Clinical Trials Day. To mark the occasion, Gareth Griffiths, Scientific Director of our Wales Cancer Trials Unit, wrote us an article about the world-class clinical trials being carried out there. Nearly one in five cancer pa...

Bel Marra Health Supports a Recent Study Out of UCLA that Shows a Link Between Sugar and Brain HealthBel Marra Health, well known for offering high-quality, specially formulated vitamins and nutritional supplements, supports recent research that shows there is a tie between sugar and brain health. Toronto, ON (PRWEB) May 26, 2012 Bel Marra Health, well known for offering high-quality, specially formulated vitamins and nutritional supplements, supports recent research that shows there is a tie be...

Apollo Group's White Dental Clinic offers high end clinical─cosmetic procedures to save natural teethWhite Dental Clinic, an Apollo Group initiative, is offering Micro Dentistry and Snap─on─Smile which would prove to be economical in the long run for patients.

Morbidity high after percutaneous drainage for acute cholecystitisNEW YORK (Reuters Health) - Patients who had percutaneous drainage for acute cholecystitis, instead of cholecystectomy, had longer recoveries, more morbidity, and a trend toward lower survival in a retrospective study.

[Comment] Magnesium and neuroprotection in subarachnoid haemorrhageNeuroprotection in aneurysmal subarachnoid haemorrhage has been extensively investigated because of the disease's high morbidity and mortality in young adults. Neurological factors that affect clinical outcome include increased intracranial pressure...

Short Course of Drug Fails in Vent-Associated Pneumonia (CME/CE)SAN FRANCISCO (MedPage Today) -- A short course of high-dose doripenem (Doribax) for ventilator-associated pneumonia did more harm than good, and a clinical trial testing the approach was stopped early, a researcher said here.

High BMI May Reduce Efficacy of InfliximabMore research is needed to determine how fat mass influences response to infliximab in inflammatory rheumatic conditions. Medscape Medical News

First Dangerous Heat Wave of the Season Expected to Arrive this WeekendPennsylvania Departments of Health and Aging Offer Important Heat Safety Tips HARRISBURG, Pa., May 25, 2012 /PRNewswire-USNewswire/ -- With hot temperatures and high humidity expected to make an early appearance in some parts of Pennsylvania this Memorial Day weekend, the Departments of Health and Aging are urging everyone to take simple steps to prevent serious heat-related illness or...

Device May Inject Variety of Drugs Without Using NeedlesResearchers have engineered a device that delivers a tiny, high-pressure jet of medicine through the skin without the use of a hypodermic needle.

Carbon Commentary · The Rothamsted battleThis and more at The Carbon Commentary:The main benefit from the genetic modification [in the Rothamsted wheat trial] may be the reduction in the need to use synthetic insecticides. In the UK about three quarters of all wheat has an insecticide applied, according to the last government survey. Most of these fields have synthetic pyrethroids sprayed onto the crop. Artificial pyrethoids are similar...

Research roundup: Do mandatory screening laws affect disparities?; Mass. health law, 6 years laterSince Massachusetts passed its own expansive health law, the state's uninsured rate has dropped and access to care has dramatically improved. But as this brief notes, two major issues remain. Massachusetts will have to find ways to contain health car...

High TOP2B/TOP2A expression ratio at diagnosis correlates with favourable outcome for standard chemotherapy in acute myeloid leukaemia

Real Time Medical to Feature Diagnostic Imaging Software @ Innovation Showcase at e-Health 2012TORONTO, May 25, 2012 /PRNewswire/ -- Real Time Medical (http://www.realtimemedical.com), a global leader in diagnostic imaging software and service solutions, has been selected to feature its latest advancements in diagnostic imaging workflow productivity, orchestration, quality assurance and collaboration at e-Health 2012, as part of the Innovation & Interoperability Showcase. The confe...

Latent Autoimmune Diabetes in Adults Often MisdiagnosedAACE 2012: Autoantibody testing in certain patients diagnosed with type 2 diabetes can yield high numbers with latent autoimmune diabetes. Medscape Medical News

G8 leaders must follow through on food security commitments"I have just returned from a whirlwind visit to Washington, D.C., and Chicago, where I participated in a number of events around the G8 and NATO Summits focused on food and nutrition security," Tom Arnold, CEO of Concern Worldwide, writes in the Huff...

HIGH-TECH DIAGNOSETOOLS AUS ÖSTERREICH SIND EUROPAREIFRisikokapitalgeber tecnet unterstützt Anagnostics´ Technologie zur In-vitro-Diagnostik St. Pölten / St. Valentin, 24. Mai 2012 – Ob Drogen im Urin oder Mutationen in tumor-relevanten Genen – mit einer neu entwickelten Diagnosemethode s...

Dueling student loan bills stall in SenateNeither measure reached the 60-vote threshold needed to delay an interest rate increase for 7.4 million students with college loans. Republicans want to pay for it by abolishing a preventive health program in the health care law; Democrats proposed r...

Phone contact with nurses linked with better outcomes for women with gestational diabetesAmong women with gestational diabetes mellitus, referral to a telephone-based nurse management program was associated with lower risk of high baby birth weight and increased postpartum glucose testing, according to Kaiser Permanente researchers.

Wound Care Publication to be Distributed Within USA Today Highlights Advancements In The Industry and Inspirational Survival Story From J.R. MartinezNEW YORK, May 25, 2012 /PRNewswire/ -- Mediaplanet Publishing, the global leader in theme media, today publishes Wound Care, an eight-page section distributed within the USA Today newspaper. Reaching over 2 million readers, the special section will appear within USA Today in the high-impact markets of New York, New England, North and South Carolina, and Southern Florida with the help of a number o...

Cancer Patients Fare Well on High-Dose Sublingual FentanylA study to assess the titration of sublingual fentanyl for breakthrough cancer pain showed patients satisfied on high doses. Medscape Medical News

Telephone Contact with Nurses is Associated with Improved Outcomes for Women with Gestational DiabetesOAKLAND, Calif., May 25, 2012 /PRNewswire/ -- Among women with gestational diabetes mellitus, referral to a telephone-based nurse management program was associated with lower risk of high baby birth weight and increased postpartum glucose testing, according to Kaiser Permanente researchers. Investigators for the Kaiser Permanente Northern California Division of Research examined the associa...

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