Advertisement
Advertise here Publish your press releases here Sponsor BioPortfolio
Follow us on Twitter Sign up for daily news and research emails Contributors wanted

Muscle strength and bone density in patients with different rheumatic conditions: cross-sectional study.

11:27 EDT 24th July 2014 | BioPortfolio

Summary of "Muscle strength and bone density in patients with different rheumatic conditions: cross-sectional study."

Aim. To explore the relationship between muscle strength and bone density in patients with different rheumatic diseases and to examine whether inflammatory arthritis was more harmful for muscle strength and bone loss than degenerative joint diseases. Methods. The study included 361 men and women with a mean±standard deviation age of 60.5±11.4 years and different rheumatic conditions: regional syndromes, osteoarthritis of the hands, shoulders, knees, and hips, and inflammatory arthritis. Maximum voluntary back strength was measured by isometric dynamometry. Bone mineral density (BMD; g/cm2) of the lumbar spine, femoral neck, and distal radius was measured by dual-energy x-ray absorptiometry. Anthropometry and lifestyle characteristics were also assessed. Results. Back strength was lowest in patients with hand and shoulder osteoarthritis (20.0±17.9 kg), followed by patients with inflammatory arthritis (24.8±19.2 kg). Patients with inflammatory arthritis had the lowest BMD at the mid-radius (0.650±0.115 g/cm2) and femoral neck (0.873±0.137 g/cm2), while patients with hand and shoulder osteoarthritis had the lowest BMD at the mid-radius (0.660±0.101). In both sexes, muscle strength was significantly lower in patients who had lower BMD (T score<-1.0). Multiple regression analysis identified significant predictors of back strength to be spine BMD (P=0.024) and body mass index (P=0.004) in men and femoral neck BMD in women (P=0.004). Conclusion. Muscle strength decline may be connected to bone loss in patients with rheumatic conditions, especially those with inflammatory joint diseases.

Affiliation

Selma Cvijetic, Department for Environmental and Occupational Health; Institute for Medical Research and Occupational Health, Ksaverska cesta 2, 10001 Zagreb, Croatia, cvijetic@imi.hr.

Journal Details

This article was published in the following journal.

Name: Croatian medical journal
ISSN: 1332-8166
Pages: 164-170

Links

PubMed Articles [37496 Associated PubMed Articles listed on BioPortfolio]

The Association Between Hip Muscle Cross-Sectional Area, Muscle Strength, and Bone Mineral Density.

Studies examining the association between muscle size, muscle strength, and bone mineral density (BMD) are limited. Thus, this study aimed to describe the association between hip muscles cross-section...

Striated muscle fiber size, composition and capillary density in diabetes in relation to neuropathy and muscle strength.

Diabetic polyneuropathy (DPN) leads to progressive loss of muscle strength in the lower extremities due to muscular atrophy. Alterations in vascularization occur in diabetic striated muscle, however,...

Deficits in muscle mass, muscle density, and modified associations with fat in rheumatoid arthritis.

Purpose To quantify muscle outcomes, independent of fat mass, in rheumatoid arthritis (RA) compared to healthy controls. Methods Quantitative CT scans measured calf muscle and fat cross-sectional area...

Management of osteoporosis with calcitriol in elderly Chinese patients: a systematic review.

Osteoporosis, a skeletal disorder characterized by a reduction in bone strength, is becoming a major public health problem in the People's Republic of China, with a rapid increase observed among the p...

Upper limb muscle strength & endurance in chronic obstructive pulmonary disease.

Background & objectives: There are very few studies that have investigated the muscle strength and endurance of upper limbs (UL) in chronic obstructive pulmonary disease (COPD). We undertook this stud...

Clinical Trials [3202 Associated Clinical Trials listed on BioPortfolio]

The Effect of Exercise in Postmenopausal Women With Low Bone Density

This clinical trial aims to evaluate the effects of a 12 month gym- and home-based exercise program on bone density and falls risk factors in postmenopausal women with low bone density. It...

BHS4 - Bone/Muscle Changes Following Hip Fracture in Older White Women

The major goals of this study are: 1. To conduct an intervention development study to evaluate the feasibility of implementing an exercise intervention for reduction losses in bone...

Effect of Neutralization of Endogenous Acid Production on Bone Mineral Density and Microarchitectural Composition of Bone

Hypothesis: Neutralization of acid production induced by the Western diet with oral administration of potassium citrate increases bone mineral density and bone mass as well as skeletal mus...

Strength Training for Skeletal Muscle Adaptation After Stroke

Chronically disabled stroke survivors experience accelerated skeletal muscle atrophy and other detrimental changes to muscle and surrounding tissues on the paretic side. This unilateral ti...

The Effect of Testosterone Replacement on Bone Mineral Density in Boys and Men With Anorexia Nervosa

Decreased bone strength is a common and serious medical problem present in many people with anorexia nervosa. Men with anorexia nervosa have lower levels of gonadal steroids such as testo...

Medical and Biotech [MESH] Definitions

The amount of force generated by MUSCLE CONTRACTION. Muscle strength can be measured during isometric, isotonic, or isokinetic contraction, either manually or using a device such as a MUSCLE STRENGTH DYNAMOMETER.

The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.

A device that measures MUSCLE STRENGTH during muscle contraction, such as gripping, pushing, and pulling. It is used to evaluate the health status of muscle in sports medicine or physical therapy.

Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES.

Removal of mineral constituents or salts from bone or bone tissue. Demineralization is used as a method of studying bone strength and bone chemistry.

Search BioPortfolio: