Titanium back plate for a PMMA keratoprosthesis: clinical outcomes.

14:07 EDT 30th August 2015 | BioPortfolio

Summary of "Titanium back plate for a PMMA keratoprosthesis: clinical outcomes."

BACKGROUND/
PURPOSE:
To compare the rate of retroprosthetic membrane (RPM) formation in Boston Keratoprosthesis (BKPro) with polymethyl methacrylate (PMMA) versus titanium backplates.
DESIGN:
Retrospective comparative chart review.
METHODS:
Multicenter study population: a total of 78 eyes with keratoprosthesis implants with either PMMA or titanium backplates were included in the study. To be included in the study, all subjects had to have completed a minimum of 6-month follow-up period. Incidence of RPM development at 6-month postoperative period was noted across the study population. PMMA and titanium backplates were then compared by their rate of association with subsequent RPM.
RESULTS:
Twenty-three out of 55 eyes (41.8%) with PMMA backplates and three out of 23 eyes (13.0%) with titanium backplates had developed an RPM at 6 months after implantation. The titanium backplates were associated with significantly less RPM formation than PMMA backplates (p = 0.014, Chi-square test).
CONCLUSIONS:
Titanium seems to be associated with less RPM formation than PMMA when used as a material for the BKPro back plate.

Affiliation

Cornea Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA, 02114, USA.

Journal Details

This article was published in the following journal.

Name: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Opht
ISSN: 1435-702X
Pages:

Links

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