Meaningful Placebos - Controlling the Uncontrollable.

06:00 EDT 15th July 2011 | BioPortfolio

Summary of "Meaningful Placebos - Controlling the Uncontrollable."

In this issue of the Journal, Wechsler et al.(1) report data from a study that compared four interventions involving patients with asthma ( number, NCT01143688). They found that three of the interventions - active albuterol, sham albuterol, and sham acupuncture - were all equally effective in controlling asthma symptoms, as judged by patient-reported improvement. In contrast, lung function was improved only in those given active albuterol, as measured by an increase in the forced expiratory volume in 1 second (FEV(1)). The fourth intervention was "no treatment," in which patients were told to wait for several hours and then . . .


From the University of Michigan-Dearborn, Dearborn.

Journal Details

This article was published in the following journal.

Name: The New England journal of medicine
ISSN: 1533-4406
Pages: 171-172


PubMed Articles [2683 Associated PubMed Articles listed on BioPortfolio]

The use of placebos in phase III clinical trials in Brazil.

In 2008, Brazil's Federal Council of Medicine [Conselho Federal de Medicina] (CFM) - regulatory and supervisory agency on the ethical practice of medicine - banned the participation of Brazilian docto...


-This study tested Antonovsky's postulate that a high sense of coherence (SOC) helps people avoid negative life events. It was assumed that negative life events that were uncontrollable would not show...

Hyperbaric medicine and the placebo effect.

The placebo in medicine has a long and interesting history. Despite the widespread use of placebo medication and sham interventions in clinical research, surprisingly little is known about how placebo...

Coping Among Individuals With Multiple Sclerosis: Evaluating a Goodness-of-Fit Model.

Multiple sclerosis (MS) is a chronic illness involving both controllable and uncontrollable stressors. The goodness-of-fit hypothesis posits that managing stressors effectively requires the use of dif...

Anticipated Survival and Health Behaviours in Older English Adults: Cross Sectional and Longitudinal Analysis of the English Longitudinal Study of Ageing.

Individuals may make a rational decision not to engage in healthy behaviours based on their assessment of the benefits of such behaviours to them, compared to other uncontrollable threats to their hea...

Clinical Trials [406 Associated Clinical Trials listed on BioPortfolio]

Activated Protein C and Corticosteroids for Human Septic Shock

This study aims at comparing the efficacy and safety of recombinant human activated protein C to that of low dose of corticosteroids and at investigating the interaction between these drug...

Standard Pain Control or Intrathecal Therapy in Controlling Pain in Patients With Locally Advanced, Unresectable, or Metastatic Pancreatic Cancer

RATIONALE: Giving medications in different ways may change their effectiveness in controlling pain. It is not yet known whether intrathecal therapy is more effective than standard therapy ...

Workplace Productivity of Persons Who Use Controlling Behavior With Intimate Partners

The goal of this project is to pilot-test an instrument that is designed to assess the relationship between persons who use controlling behavior with intimate partners, as a risk factor fo...

Examining Factors That May Influence Resistance to HIV-1 Infection

Some people who are exposed to the HIV-1 virus are capable of either controlling or completely preventing viral infection. Multiple genetic factors may contribute to preventing or controll...

Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy

RATIONALE: Acupressure wristbands may prevent or reduce nausea and caused by chemotherapy. It is not yet known whether standard care is more effective with or without acupressure wristband...

Medical and Biotech [MESH] Definitions

Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.

Those factors, such as language or sociocultural relationships, which interfere in the meaningful interpretation and transmission of ideas between individuals or groups.

The enhancement of physical, cognitive, emotional and social skills so an individual may participate in chosen activities. Recreational modalities are used in designed intervention strategies, incorporating individual's interests to make the therapy process meaningful and relevant.

Injuries of tissue other than bone. The concept is usually general and does not customarily refer to internal organs or viscera. It is meaningful with reference to regions or organs where soft tissue (muscle, fat, skin) should be differentiated from bones or bone tissue, as "soft tissue injuries of the hand".

Methods for controlling genetic SEX of offspring. It may include SEX DETERMINATION (GENETICS) and other means.


Relevant Topics

Latest News Clinical Trials Research Drugs Reports Corporate
Pulmonary relating to or associated with the lungs eg Asthma, chronic bronchitis, emphysema, COPD, Cystic Fibrosis, Influenza,  Lung Cancer, Pneumonia, Pulmonary Arterial Hypertension, Sleep Disorders etc Follow and track Lung Cancer News ...

Alternative Medicine
Latest News Clinical Trials Research Drugs Reports Corporate
Complementary and alternative medicine (CAM) is the term for medical products and practices that are not part of standard care. Standard care is what medical doctors, doctors of osteopathy, and allied health professionals, such as nurses and physical the...

Latest News Clinical Trials Research Drugs Reports Corporate
Asthma is caused by inflammation of small tubes, called bronchi, which carry air in and out of the lungs. If you have asthma, the bronchi will be inflamed and more sensitive than normal.  When you come into contact with something that irritates your...

Searches Linking to this Article