The Early Repolarization Pattern: What's in the Name?
Summary of "The Early Repolarization Pattern: What's in the Name?"
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This article was published in the following journal.
Name: Journal of the American College of Cardiology
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21996400
- DOI: http://dx.doi.org/10.1016/j.jacc.2011.06.053
Endogenous late Na(+) current (INaL) is proarrhythmic in conditions where repolarization reserve is reduced. We tested the hypothesis that selective inhibition of endogenous INaL stabilizes cardiac re...
QT prolongation is a risk factor for proarrhythmia when beginning antiarrhythmic drug therapy (AAD). However, there are no data regarding monitoring repolarization changes during a ventricular paced (...
What neural mechanisms underlie the ability to attend to a complex object in the presence of competing overlapping stimuli? We evaluated whether object-based attention might involve pattern-specific f...
Sepiapterin reductase deficiency (SRD; Online Mendelian Inheritance in Man *182125) is a rare disorder of biogenic amines synthesis caused by mutations of the SPR gene on chromosome 2p14-p12.(1) The m...
The purpose of this study is to determine whether HKI-272 affects the rhythms of the heart (cardiac repolarization).
This study evaluates whether YM443 causes any changes in the electrocardiogram of healthy adults.
To assess the effect of ERB-041 after multiple oral doses on cardiac repolarization as assessed by the QTc interval.
The purpose of this study is to examine the effect of SKI-606 on rhythms of the heart (cardiac repolarization)
A consequence of chronic RV pacing is a process of electrical remodeling that alters myocardial repolarization to reflect the altered depolarization induced by the RV lead. When RV pacing...
Medical and Biotech [MESH] Definitions
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Methods to determine in patients the nature of a disease or disorder at its early stage of progression. Generally, early diagnosis improves PROGNOSIS and TREATMENT OUTCOME.
The analysis of a critical number of sensory stimuli or facts (the pattern) by physiological processes such as vision (PATTERN RECOGNITION, VISUAL), touch, or hearing.
A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)
A personality disorder whose essential feature is a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. The individual must be at least age 18 and must have a history of some symptoms of CONDUCT DISORDER before age 15. (From DSM-IV, 1994)