Convulsions Associated with the Use of a Synthetic Cannabinoid Product.

18:50 EDT 20th October 2014 | BioPortfolio

Summary of "Convulsions Associated with the Use of a Synthetic Cannabinoid Product."


INTRODUCTION:
Clinical presentations following the use of various "spice" or synthetic cannabinoids have included agitation, anxiety, emesis, hallucinations, psychosis, tachycardia, and unresponsiveness. Convulsions were described in a one report although there was not laboratory confirmation for synthetic cannabinoids. In another published report laboratory confirmation for a synthetic cannabinoid was done in which the patient manifested activity that was interpreted as a possible convulsion. CASE
REPORT:
We describe a patient who had two witnessed generalized convulsions soon after smoking a "spice" product that we later confirmed to have four different synthetic cannabinoids.
DISCUSSION:
Convulsions have only rarely been associated with marijuana exposures. Recreational use of synthetic cannabinoids is a very recent phenomenon and there is a very limited, albeit burgeoning, literature detailing the associated complications including convulsions we have reported here. The absence of anticonvulsant phytocannabinoids in spice products could potentially be one of multiple unknown mechanisms contributing to convulsions.

Affiliation

Division of Medical Toxicology, Department of Emergency Medicine, University of California, San Diego Medical Center, 200 West Arbor Drive #8925, San Diego, CA, 92103, USA, aschneir@ucsd.edu.

Journal Details

This article was published in the following journal.

Name: Journal of medical toxicology : official journal of the American College of Medical Toxicology
ISSN: 1937-6995
Pages:

Links

PubMed Articles [4645 Associated PubMed Articles listed on BioPortfolio]

Enzyme-Linked Immunosorbent Assay (ELISA) for the Detection of Use of the Synthetic Cannabinoid Agonists UR-144 and XLR-11 in Human Urine.

Ongoing changes in the synthetic cannabinoid drug market create the need for relevant targeted immunoassays for rapid screening of biological samples. We describe the validation and performance charac...

'Crazy Monkey' Poisons Man and Dog: Human and canine seizures due to PB-22, a novel synthetic cannabinoid.

Context. Synthetic cannabinoids have been manufactured, sold, and consumed for recreational purposes since at least 2004; their use has been associated with adverse psychiatric, cardiovascular, renal,...

A survey of synthetic cannabinoid consumption by current cannabis users.

ABSTRACT. Background: Despite growing concern about the increased rates of synthetic cannabinoid (SC) use and their effects, only limited data are available that addresses these issues. This study ass...

Detection of the synthetic cannabinoid JWH-210 in the Valencia region.

A Gut Gone to Pot: A Case of Cannabinoid Hyperemesis Syndrome due to K2, a Synthetic Cannabinoid.

Cannabinoid Hyperemesis Syndrome (CHS) was first described in 2004. Due to its novelty, CHS is often unrecognized by clinicians leading to expensive workup of these patients with cyclical symptoms. It...

Clinical Trials [744 Associated Clinical Trials listed on BioPortfolio]

Deep Brain Stimulation Effects Study

The purpose of this study is to provide proof-of-concept that the test product can perform as intended in an intra-operative setting and the responses to the test product are perceivable i...

Lindi Product Satisfaction Survey

This study is being done because the investigators would like to evaluate product satisfaction of three test products (product A, product B, product C) that are available at any drug store...

Comparasion of Two Urostomy Bags (2-Piece).

Coloplast A/S has developed a new, improved two-piece product for people with urostomies. This 2-piece product is a part of a new product family, under the brand name SenSura. The aim of t...

Nabilone for the Treatment of Phantom Limb Pain

The purpose of this proposed study is to conduct a randomized double-blind placebo controlled trial assessing the benefit of nabilone in pain management and improvement of quality of life ...

Prediction and Testing of Antigenic Sites of the AIDS Virus, HTLV-III Recognized by T Lymphocytes for the Development of Synthetic Vaccines

Subjects are healthy adult volunteers either at high risk for HIV infection or already known to be seropositive, who will donate blood for in vitro tests of T-cell function and in vitro re...

Medical and Biotech [MESH] Definitions

A subclass of cannabinoid receptor found primarily on immune cells where it may play a role modulating release of CYTOKINES.

A subclass of cannabinoid receptor found primarily on central and peripheral NEURONS where it may play a role modulating NEUROTRANSMITTER release.

Form in which product is processed or wrapped and labeled. PRODUCT LABELING is also available.

Analogs or derivatives of prostaglandin A that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal PGA.

Analogs or derivatives of prostaglandins E that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal PGE.

Search BioPortfolio:
Loading
Advertisement

Relevant Topic

Psychiatry
Latest News Clinical Trials Research Drugs Reports Corporate
Psychiatry is the study of mental disorders and their diagnosis, management and prevention.  Conditions include schizophrenia, severe depression and panic disorders among others. There are pharmaceutical treatments as well as other therapies to help...

Advertisement

Searches Linking to this Article