Advertisement

Topics

Thrombosis prophylaxis in geriatric patients.

06:00 EDT 24th March 2012 | BioPortfolio

Summary of "Thrombosis prophylaxis in geriatric patients."

Older, multimorbid patients carry a high risk of suffering from a thromboembolic disease. The incidence of deep vein thrombosis in the outpatient setting is, depending on age, between 71 and 132 cases per 100,000 inhabitants and year. The rates increase significantly in the hospital setting and with increasing age. Today, pharmacological thrombolytic prophylaxis is the gold standard in patients needing surgical and internal medical care and is described in international evidence-based guidelines. However, the percentage of patients, who despite the guidelines do not receive pharmacological thrombolytic prophylaxis, is still very high. This is especially true for the group of multimorbid, very old patients. In the present work, the pathophysiological and clinical background for the increased susceptibility of thromboembolism in geriatric patients is summarized and the drugs currently available for pharmacological thromboembolic prophylaxis are presented. Hereby, special emphasis is placed on aspects of application in the elderly.

Affiliation

Fachbereich Geriatrie und kompetenzbasierte Curriculumsentwicklung, Medizinische Universität Graz, Auenbruggerplatz 15, 8036, Graz, Österreich, Regina.Roller-Wirnsberger@medunigraz.at.

Journal Details

This article was published in the following journal.

Name: Zeitschrift fur Gerontologie und Geriatrie
ISSN: 1435-1269
Pages:

Links

DeepDyve research library

PubMed Articles [27998 Associated PubMed Articles listed on BioPortfolio]

Late Venous Thromboembolism Prophylaxis after Craniotomy in Acute Traumatic Brain Injury.

The objective of this study is to compare rates of venous thromboembolism (VTE) in patients who receive enoxaparin prophylaxis compared with no enoxaparin prophylaxis after craniotomy for traumatic br...

Congenital factor XI and factor VII deficiencies assure an apparent opposite protection against arterial or venous thrombosis: An intriguing observation.

Objective To investigate the prevalence and type of thrombotic events reported in patients with congenital factor XI (FXI) or factor VII (FVII) deficiency. Patients and methods Data on all patients wi...

Individualizing Factor Replacement Therapy in Severe Hemophilia.

Prophylactic replacement of factor concentrate is the established optimal treatment to avoid or minimize joint disease in severe hemophilia patients, thus ultimately improving their life expectancy an...

Comparison of Chemical and Mechanical Prophylaxis of Venous Thromboembolism in Nonsurgical Mechanically Ventilated Patients.

Background. Thromboembolic events are major causes of morbidity, and prevention is important. We aimed to compare chemical prophylaxis (CP) and mechanical prophylaxis (MP) as methods of prevention in ...

Clinical factors associated with inappropriate prophylaxis of venous thromboembolic disease in critically ill patients. A single day cross-sectional study.

A poor implementation of VTE prophylactic measures recommended for critically ill patients has been observed in several epidemiological studies. The clinical factors associated with this have not been...

Clinical Trials [1138 Associated Clinical Trials listed on BioPortfolio]

Multi-Center Desirudin Utilization Trial in Patients With or Without Thrombosis Requiring an Alternative to Heparin-Based Anticoagulation

Demonstrate the clinical utility of fixed-dose SC Desirudin for the prophylaxis or treatment of thrombosis in patients in whom, in the opinion of the investigator, an alternative to hepari...

Geriatric Education and Its Effect on Certain Aspects of Hospital Care of Nursing Home Patients

Nursing home patients admitted to the hospital pose a significant challenge for health care providers. Geriatric teaching pays particular attention to these admissions and related problems...

Evaluation of Argatroban Injection in Pediatric Patients Requiring Anticoagulant Alternatives to Heparin

The purpose of this study is to evaluate the safe and effective dose of Argatroban for prophylaxis and/or treatment of thrombosis in pediatric patients with current or previous diagnosis o...

Efficacy of an Active Geriatric Evaluation for Geriatric Syndromes to Prevent Functional Decline in Family Medicine

This study aims to test the efficacy of a comprehensive assessment and management tool (AGE: Active Geriatric Evaluation) for geriatric syndromes to prevent functional decline in elderly p...

Early Geriatric Follow-up in Older Acute Medical Patients

The study is a quasi-randomized controlled trial conducted in a Danish University Hospital including older patients admitted to Emergency Department (ED). 'Early geriatric follow-up' is a ...

Medical and Biotech [MESH] Definitions

An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.

A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.

Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.

DEEP VEIN THROMBOSIS of an upper extremity vein (e.g., AXILLARY VEIN; SUBCLAVIAN VEIN; and JUGULAR VEINS). It is associated with mechanical factors (Upper Extremity Deep Vein Thrombosis, Primary) secondary to other anatomic factors (Upper Extremity Deep Vein Thrombosis, Secondary). Symptoms may include sudden onset of pain, warmth, redness, blueness, and swelling in the arm.

Tight coverings for the foot and leg that are worn to aid circulation in the legs and prevent the formation of EDEMA and DEEP VEIN THROMBOSIS. PNEUMATIC COMPRESSION STOCKINGS serve a similar purpose especially for bedridden patients and following surgery.

Quick Search
Advertisement
 


DeepDyve research library

Searches Linking to this Article