Chronic spontaneous urticaria: an autoimmune disease? A revision of the literature.

04:53 EDT 3rd September 2015 | BioPortfolio

Summary of "Chronic spontaneous urticaria: an autoimmune disease? A revision of the literature."

The cause of chronic spontaneous urticaria has been an enigma for decades, but the recognition of functional autoantibodies in some patients with the spontaneous chronic urticaria has opened up a new concept of autoimmune urticaria. Clinical and laboratory features are in keeping with an autoimmune aetiology for many patients with otherwise inexplicable disease, but there is still debate about the importance of functional autoantibodies in the disease pathogenesis, how to test them and the clinical implications for treatment and prognosis. This review will look at the evidence for there being an autoimmune subset of urticaria, the strengths and weaknesses of the available tests in current use.

Affiliation

Dipartimento di Medicina Interna e Specialistica (DIMIS), Università degli Studi di Palermo, Via del Vespro, 141, 90127, Palermo, Italy, gabriele.dilorenzo@unipa.it.

Journal Details

This article was published in the following journal.

Name: Clinical and experimental medicine
ISSN: 1591-9528
Pages:

Links

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Medical and Biotech [MESH] Definitions

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Chronic autoimmune thyroiditis, characterized by the presence of high serum thyroid AUTOANTIBODIES; GOITER; and HYPOTHYROIDISM.


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Autoimmune disorders are conditions that occurs when the immune system mistakenly attacks and destroys healthy body tissue. There are more than 80 different types of autoimmune disorders. Normally the immune system's white blood cells help protect ...

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