Knee biomechanics during walking gait following matrix-induced autologous chondrocyte implantation.
Summary of "Knee biomechanics during walking gait following matrix-induced autologous chondrocyte implantation."
Matrix-induced autologous chondrocyte implantation is a technique for repairing articular cartilage defects in the knee. Despite reported improvements in pain, little is known about the recovery of knee biomechanics during walking gait.
A randomized controlled study design was used to investigate knee biomechanics during gait in 61 patients following matrix-induced autologous chondrocyte implantation, in conjunction with either 'accelerated' or 'traditional' approaches to post-operative weight-bearing rehabilitation. Gait analysis was performed at 3, 6 and 12months post-surgery in both patient groups, and two matched, unaffected control groups for comparison.
The spatiotemporal and ground reaction force parameters were similar between patient groups and their respective control groups at all time points. When compared with controls, both patient groups demonstrated significantly reduced knee extension moments up until, and including, 12months. The traditional group demonstrated a significantly reduced knee adduction moment at 3, 6 and 12months, and a significantly reduced knee flexion moment at 3months. There were no differences in these knee moments between the accelerated patient group and controls.
Overall, a higher level of gait dysfunction was observed in patients who underwent traditional rehabilitation. Future research is needed to investigate the recovery of normal gait following matrix-induced autologous chondrocyte implantation, and its effect on repair tissue development.
School of Sport Science, Exercise and Health, University of Western Australia, Crawley, Perth, Western Australia, 6009.
This article was published in the following journal.
Name: Clinical biomechanics (Bristol, Avon)
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20692745
- DOI: http://dx.doi.org/10.1016/j.clinbiomech.2010.07.004
Osteoarthritis of the knee affects millions of people. Elastic knee sleeves aim at relieving symptoms. While symptomatic improvements have been demonstrated as a consequence of elastic knee sleeves, e...
Using functional near-infrared spectroscopy, we investigated cortical activation while participants observed their own gait and the gait of others. Further, we compared the vividness of motor imagery ...
Lower-limb multi-joint (knee and ankle) stiffness may play an important role in functional activities such as walking, and may be significantly altered post stroke. Thus, determination of lower-limb m...
Fatigue and ageing contribute to impaired control of walking and are linked to falls. In this project, fatigue was induced by maximum speed walking to examine fatigue effects on lower limb trajectory ...
The prevalence of medial knee osteoarthritis is greater in females, and is associated with varus knee alignment. During gait, medial knee osteoarthritis has been linked to numerous alterations. Intere...
Weight is a risk factor for knee osteoarthritis Knee osteoarthritis is associated with abnormal gait biomechanics Gait biomechanics are evaluated in gastric bypass patients before and af...
Stiff knee gait is a common gait dysfunction following acquired brain injury. This gait deviation is characterized by reduced knee flexion during swing phase of the gait cycle and adversel...
The goal of this project is to assess the effects of an ankle strap on the effectiveness of a laterally-wedged insole with ankle strapping in reducing knee symptoms and improving static an...
The objective of this study is to compare the effect on gait of unicompartmental knee arthroplasty (UKA), using the Oxford® Partial Knee, versus total knee arthroplasty (TKA), using the V...
The purpose of this preliminary substudy to the parent study "Aerobic Exercise Intervention for Knee Osteoarthritis" is to determine the repeatability and reproducibility of various measur...
Medical and Biotech [MESH] Definitions
Manner or style of walking.
An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.
Impairment of the ability to coordinate the movements required for normal ambulation (WALKING) which may result from impairments of motor function or sensory feedback. This condition may be associated with BRAIN DISEASES (including CEREBELLAR DISEASES and BASAL GANGLIA DISEASES); SPINAL CORD DISEASES; or PERIPHERAL NERVOUS SYSTEM DISEASES.
Injuries to the knee or the knee joint.
Replacement for a knee joint.