Evolution from macular pseudohole to lamellar macular hole - spectral domain OCT study.
Summary of "Evolution from macular pseudohole to lamellar macular hole - spectral domain OCT study."
The pathogenesis of macular pseudohole (MPH) is supposed to be different from that of macular lamellar hole (LMH). MPH is thought to be caused by centripetal contraction of previously present epiretinal membrane. LMH is considered to be an effect of abortive process of full-thickness macular hole formation, or a result of de-roofing of a foveal cyst in persistent cystoid macular oedema. In most cases of LMH, epiretinal membranes are present. The aim of this paper is to show that LMH and MPH may have a common origin and that LMH may evolve from MPH as an epiretinal membrane contracts.
Observational two-case series of patients with MPH and epiretinal membrane. Spectral domain optical coherence tomography (SD-OCT) was performed during follow-up.
In 6 months of follow-up in case 1 and 2 months in case 2, MPH progressed to non-full-thickness macular defect, fulfilling the criterion of LMH in SD-OCT. Non-vitreous interface traction was detected.
SD-OCT proves that MPH may progress to LMH without any vitreous traction. Progressive contraction of epiretinal membranes may be a cause of both MPH and LMH, being an advanced stage of the same non-full-thickness macular disorder.
Klinika Okulistyczna "Jasne Blonia", ul. Rojna 90, 91-134, Lodz, Poland, firstname.lastname@example.org.
This article was published in the following journal.
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20703497
- DOI: http://dx.doi.org/10.1007/s00417-010-1463-1
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Medical and Biotech [MESH] Definitions
A form of MACULAR DEGENERATION also known as dry macular degeneration marked by occurrence of a well-defined progressive lesion or atrophy in the central part of the RETINA called the MACULA LUTEA. It is distinguishable from WET MACULAR DEGENERATION in that the latter involves neovascular exudates.
Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)
Specialized ophthalmic technique used in the surgical repair and or treatment of disorders that include retinal tears or detachment; MACULAR HOLES; hereditary retinal disease; AIDS-related retinal infections; ocular tumors; MACULAR DEGENERATION; DIABETIC RETINOPATHY; and UVEITIS.
Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.
A macular lesion on the side of the FACE, involving the CONJUNCTIVA and EYELIDS, as well as the adjacent facial skin, SCLERA; OCULOMOTOR MUSCLES; and PERIOSTEUM. Histological features vary from those of a MONGOLIAN SPOT to those of a BLUE NEVUS.