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Paracetamol overdose.

08:00 EDT 14th August 2013 | BioPortfolio

Summary of "Paracetamol overdose."

Acetaminophen is the most widely used analgesic-antipyretic and is available as an over-the-counter medication in many countries. Although generally safe at usual therapeutic doses, acetaminophen may cause hepatic toxicity in case of chronic or acute overuse and even at therapeutic doses in susceptible individuals. The aim of this article is to review the mechanisms of acetaminophen toxicity and to review the critical steps in the management of acute or chronic acetaminophen intoxication.

Affiliation

Service des urgences, Département de médecine communautaire, de premier recours et des urgences, HUG, 1211 Genève 14. majd.ramlawi@hcuge.ch

Journal Details

This article was published in the following journal.

Name: Revue médicale suisse
ISSN: 1660-9379
Pages: 1478-82

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Medical and Biotech [MESH] Definitions

An accidental or deliberate dose of a medication or street drug that is in excess of what is normally used.

Accidental or deliberate use of a medication or street drug in excess of normal dosage.

A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.

A central nervous system stimulant. It was formerly used in the treatment of barbiturate overdose but is now considered to be of no value for such purposes and may be dangerous. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1229)

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