Advertisement

Topics

Chronic frontal sinus disease: Combined use of platelet-rich plasma and calvarial bone grafts for sinus obliteration in aggressive and secondary cases.

Summary of "Chronic frontal sinus disease: Combined use of platelet-rich plasma and calvarial bone grafts for sinus obliteration in aggressive and secondary cases."


INTRODUCTION:
The surgical management of chronic frontal sinusitis can be challenging. The most effective way to treat this condition is sinus obliteration. Several methods have been published. We evaluated the feasibility of a combined treatment, consisting of platelet-rich plasma (PRP) and autologous calvarial bone chips, in chronic frontal sinus diseases (CFSD). PATIENTS AND
METHODS:
From January2001 to June2006, seven patients (four women and three men) were admitted presenting with signs and symptoms of CFSD. Their ages ranged from 35 to 67years. Two patients presented with signs of frontal osteomyelitis and a cutaneous fistula, while endoscopic drainage had failed for five patients. All patients were treated by sinus obliteration though bicoronal access. Free autologous calvarial bone graft combined with PRP was used to repair the frontal sinus.
RESULTS:
The frontal sinus repair was successful in all seven patients with progressive resolution of symptoms without perioperative complication. The CT scans at 12 postoperative months showed complete obliteration of sinuses.
DISCUSSION:
Combined PRP and autologous bone graft is a safe and reliable procedure for frontal sinus obliteration. The low rate of complications and the absence of donor site morbidity support using this technique in secondary and particularly complex cases.

Affiliation

Unità Operativa Semplice di Chirurgia Maxillo-Facciale di Pronto Soccorso, AORN "Antonio Cardarelli", Napoli, Italy.

Journal Details

This article was published in the following journal.

Name: Revue de stomatologie et de chirurgie maxillo-faciale
ISSN: 1776-257X
Pages:

Links

DeepDyve research library

PubMed Articles [27863 Associated PubMed Articles listed on BioPortfolio]

Autologous platelet-rich plasma for treating chronic wounds.

Autologous platelet-rich plasma (PRP) is a treatment that contains fibrin and high concentrations of growth factors with the potential to improve the healing of chronic wounds. This is the first updat...

Combined autologous platelet-rich plasma with microneedling verses microneedling with distilled water in the treatment of atrophic acne scars: a concurrent split-face study.

Acne scarring causes cosmetic discomfort, depression, low self-esteem and reduced quality of life. Microneedling is an established treatment for scars, although the efficacy of platelet-rich plasma (P...

Is platelet-rich plasma right for your patient?

Many pro athletes claim that platelet-rich plasma has improved their performance and saved their careers. But is it right for your patients? And if so, which ones?

Effect of Topical Platelet-Rich Plasma on Burn Healing After Partial-Thickness Burn Injury.

BACKGROUND To investigate the effects of platelet-rich plasma on tissue maturation and burn healing in an experimental partial-thickness burn injury model. MATERIAL AND METHODS Thirty Wistar albino ra...

Platelet-rich plasma stimulates dermal microvascular endothelial cells and adipose derived stem cells after external radiation.

Platelet-rich plasma (PRP) products are currently suggested in the treatment of chronic wounds due to possible pro-angiogenic effects. Microvascular compromise represents the major component in radiog...

Clinical Trials [9237 Associated Clinical Trials listed on BioPortfolio]

Evaluate the Clinical Effectiveness of RegenKit Platelet-rich Plasma (PRP) in Androgenetic Alopecia Treatment

Platelet rich plasma (PRP) therapy is a novel therapeutic modality that has seen broad applications for a number of medical indications including those in orthopedics, dentistry, and derma...

Prospective Trial of Autologous Platelet Rich Plasma in Aortic Surgery

The purpose of this study is to determine whether autologous platelet rich plasma (APRP)is effective in reducing allogeneic blood transfusions during aortic surgery using deep hypothermic ...

Synovial Fluid Molecular and Stem Cell Response to Platelet Rich Plasma in Knee Osteoarthritis With Clinical and Imaging Outcome Correlation: Proof of Concept Study

The purpose of this study is to evaluate the affect that platelet rich plasma has on the molecular an cellular functioning of the knee joint.

The Effect of Platelet Rich Plasma for Carpal Tunnel Syndrome

The platelet rich plasma (PRP) is a new and potential treatment for patients with kinds of musculoskeletal disorders. Although few studies have showed beneficial effect of PRP for regenera...

Impact of Autologous Platelet Rich Plasma on Healing of Rotator Cuff Repairs

Partial-thickness and full-thickness rotator cuff tears are common soft-tissue conditions that often require surgical treatment. Initial efforts to improve tendon healing centered on impro...

Medical and Biotech [MESH] Definitions

Air-filled spaces located within the bones around the NASAL CAVITY. They are extensions of the nasal cavity and lined by the ciliated NASAL MUCOSA. Each sinus is named for the cranial bone in which it is located, such as the ETHMOID SINUS; the FRONTAL SINUS; the MAXILLARY SINUS; and the SPHENOID SINUS.

A preparation consisting of PLATELETS concentrated in a limited volume of PLASMA. This is used in various surgical tissue regeneration procedures where the GROWTH FACTORS in the platelets enhance wound healing and regeneration.

One of the paired, but seldom symmetrical, air spaces located between the inner and outer compact layers of the FRONTAL BONE in the forehead.

Inflammation of the NASAL MUCOSA in the FRONTAL SINUS. In many cases, it is caused by an infection of the bacteria STREPTOCOCCUS PNEUMONIAE or HAEMOPHILUS INFLUENZAE.

A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident.

Quick Search
Advertisement
 


DeepDyve research library

Relevant Topics

Blood
Blood is a specialized bodily fluid that delivers necessary substances to the body's cells (in animals) – such as nutrients and oxygen – and transports waste products away from those same cells.  In vertebrates, it is composed of blo...

Osteoporosis
Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...


Searches Linking to this Article