Advertisement
Advertise here Publish your press releases here Sponsor BioPortfolio
Follow us on Twitter Sign up for daily news and research emails Contributors wanted

Glutathione-stabilized magic-number silver cluster compounds.

20:45 EDT 17th April 2014 | BioPortfolio

Summary of "Glutathione-stabilized magic-number silver cluster compounds."

Magic-number theories, developed to explain the anomalous stability of clusters in the gas phase, are being successfully applied to explain the stability of families of condensed phase Au clusters. To test the generalizability of these theories, we have synthesized a family of magic-numbered Ag clusters. Silver clusters ligated with glutathione (GSH) were synthesized by reduction of silver glutathiolate in water and then separated by polyacrylamide gel electrophoresis (PAGE). The raw synthetic product consisted of a family of discrete Ag:SG clusters, each forming a band in the PAGE gel. Varying reaction conditions changed the relative abundance of the family members but not their positions and colors within the gel, indicating the molecular precision of magic-number clusters. Absorption onsets for the most abundant clusters monotonically decreased with increasing cluster size, and spectra contained a small number of peaks that corresponded to single electron transitions. Although these Ag:SG clusters are related to Au:SG clusters, the distribution of cluster sizes and the optical absorption spectra were markedly different for the two families. This suggests that the Ag:SG clusters are not a simple extension of the Au:SG system, possibly due to differences in Au and Ag chemistry. Alternatively, condensed-phase magic-number cluster theories may need to be more complex than currently believed.

Affiliation

Department of Chemistry, The University of Toledo, Toledo, Ohio 43606, USA.

Journal Details

This article was published in the following journal.

Name: Journal of the American Chemical Society
ISSN: 1520-5126
Pages: 13141-3

Links

PubMed Articles [7269 Associated PubMed Articles listed on BioPortfolio]

Nanoscale Molecular Silver Cluster Compounds in Gram Quantities.

All that's nano is not gold: Definite, crystalline molecular compounds of noble metals have been known for gold for the last few years. Now a simple synthesis of a nanoscale silver cluster compound co...

Assessment of silver nanoparticle-induced physiological and molecular changes in Arabidopsis thaliana.

In this study, the effect of silver nanoparticles and silver ions on Arabidopsis thaliana was investigated at physiological and molecular levels. The seedlings were grown in sublethal concentrations o...

Spatially marking and quantitatively counting membrane immunoglobulin M in live cells via Ag cluster-aptamer probes.

A probe composed of an aptamer and a silver cluster, where the aptamer targets mIgM of live cells and the silver cluster provides fluorescent imaging and mass quantification of mIgM of live cells, is...

Carbon Dioxide Incorporation into Alkyne Compounds Mediated by Silver Catalysts.

We have reported that a silver catalyst with a base was an effective system for the incorporation and utilization of carbon dioxide in organic syntheses under mild reaction conditions. The C≡C tripl...

Bovine serum albumin-confined silver nanoclusters as fluorometric probe for detection of biothiols.

Fluorescent bovine serum albumin-confined silver nanoclusters (BSA-AgNCs) were demonstrated to be a novel and environmentally friendly probe for the rapid detection of biothiols such as cysteine (Cys)...

Clinical Trials [891 Associated Clinical Trials listed on BioPortfolio]

Study of Glutathione, Vitamin C and Cysteine in Children With Autism and Severe Behavior Problems

This is a double-blind, placebo-controlled crossover study to evaluate the safety and efficacy of glutathione alone or glutathione, vitamin C and NAC treatment in children with autism who...

The Treatment of Bartholin´s Cyst or Abscess With Silver Nitrate

Silver nitrate treatment of Bartholin's cyst or abscess will be compared to marsupialization treatment. It is expected that silver nitrate treatment is effective, simple, inexpensive and...

Silver-Coated Endotracheal Tube to Reduce Ventilator Associated Pneumonia (VAP)

The purpose of this study is to determine if the use of a silver-coated endotracheal tube (ETT) can reduce the incidence and/or delay the time of onset of VAP when compared to a non silver...

Magic Mouthwash Plus Sucralfate Versus Benzydamine Hydrogen Chloride (HCl) for the Treatment of Radiation-Induced Mucositis

Radiation treatment is very effective for treating cancers of the head and neck, however, during the course of treatment, it is common for patients to experience soreness of their mouth an...

Study of Hypothalamic Metabolism in Spontaneous Cluster Headache Attacks

Cluster headache is characterized by unilateral excruciating head pain and autonomic dysfunction. Hypothalamic overactivity was observed in nitrate-induced cluster-headache and in only one...

Medical and Biotech [MESH] Definitions

Inorganic compounds that contain silver as an integral part of the molecule.

Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.

Compounds of silver and proteins used as topical anti-infective agents.

The use of silver, usually silver nitrate, as a reagent for producing contrast or coloration in tissue specimens.

Catalyzes the oxidation of GLUTATHIONE to GLUTATHIONE DISULFIDE in the presence of NADP+. Deficiency in the enzyme is associated with HEMOLYTIC ANEMIA. Formerly listed as EC 1.6.4.2.

Search BioPortfolio: