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12:43 EDT 13th October 2015 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 26–50 of 1,100+


-This study compared 45 yoga practitioners (M age = 29.7 yr., SD = 6.4) and 45 matched controls (M age = 29.3 yr., SD = 6.2) on the performance of a behavioral task that assessed negative emotion interference during a high- and a low-attentional demand condition, as well as on state and trait anxiety scores. Outcomes were also compared between beginner and advanced practitioners. For the behavioral task, the final sample comprised 36 yoga and 38 control participants. The yoga group presented lower emotion i...

Young drivers' responses to anti-speeding advertisements: Comparison of self-report and objective measures of persuasive processing and outcomes.

Self-report measures are typically used to assess the effectiveness of road safety advertisements. However, psychophysiological measures of persuasive processing (i.e., skin conductance response [SCR]) and objective driving measures of persuasive outcomes (i.e., in-vehicle GPS devices) may provide further insights into the effectiveness of these advertisements. This study aimed to explore the persuasive processing and outcomes of two anti-speeding advertisements by incorporating both self-report and objecti...

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers.

YAP1 is a major effector of the Hippo pathway and a well-established oncogene. Elevated YAP1 activity due to mutations in Hippo pathway components or YAP1 amplification is observed in several types of human cancers. Here we investigated its genomic binding landscape in YAP1-activated cancer cells, as well as in non-transformed cells. We demonstrate that TEAD transcription factors mediate YAP1 chromatin-binding genome-wide, further explaining their dominant role as primary mediators of YAP1-transcriptional a...

Yeast diversity on grapes in two German wine growing regions.

The yeast diversity on wine grapes in Germany, one of the most northern wine growing regions of the world, was investigated by means of a culture dependent approach. All yeast isolates were identified by sequence analysis of the D1/D2 domain of the 26S rDNA and the ITS region. Besides Hanseniaspora uvarum and Metschnikowia pulcherrima, which are well known to be abundant on grapes, Metschnikowia viticola, Rhodosporidium babjevae, and Curvibasidium pallidicorallinum, as well as two potentially new species re...

Yet another time about time … Part I: An Essay on the Phenomenology of Physical Time.

This paper presents yet another personal reflection on one the most important concepts in both science and the humanities: time. This elusive notion has been not only bothering philosophers since Plato and Aristotle. It goes throughout human history embracing all analytical and creative (anthropocentric) disciplines. Time has been a central theme in physical and life sciences, philosophy, psychology, music, art and many more. This theme is known with a vast body of knowledge across different theories and ca...

Young adults: beloved by food and drink marketers and forgotten by public health?

Young adults are a highly desirable target population for energy-dense, nutrient-poor (EDNP) food and beverage marketing. But little research, resources, advocacy and policy action have been directed at this age group, despite the fact that young adults are gaining weight faster than previous generations and other population groups. Factors such as identity development and shifting interpersonal influences differentiate young adulthood from other life stages and influence the adoption of both healthy and un...

You Say STD…..

Young Age and Aggressive Treatment in Colon Cancer.

Youth Safeguards, Budget Boons.

TMA, the Texas Public Health Coalition, and diligent physicians earned significant public health victories during the Texas Legislature's 2015 session in their drive to reduce tobacco and electronic cigarette use and to protect schoolchildren at risk for anaphylaxis.

Young women post-MI have higher plasma concentrations of interleukin-6 before and after stress testing.

Young women have poorer prognosis after myocardial infarction (MI) and a higher rate of mental stress-induced ischemia compared with similarly aged men. A higher inflammatory status may help explain these sex differences.

Yb:fiber laser-based, spectrally coherent and efficient generation of femtosecond 1.3-μm pulses from a fiber with two zero-dispersion wavelengths.

We report, to the best of our knowledge, the first experimental characterization of spectral coherence properties of wavelength conversion inside photonic crystal fibers with two zero-dispersion wavelengths (TZDWs) and demonstrate a low-noise femtosecond 1.3-μm source employing the TZDW fiber and a 1.3-W, 240-fs Yb:fiber amplifier as the seeding source. Theoretical investigation shows that pulse evolution in our TZDW fiber source is dominated by parametric amplification seeded by self-phase modulation broa...

Young Women - Problematic Patients in Vascular Surgery.

The treatment of peripheral arterial disease (PAD) in young women between 40 and 60 years of age represents a difficult challenge for the vascular surgeon. Excessive smoking, an early menopause and the unfavourable anatomic proportions of thinner arterial vessels or vein grafts during peripheral bypass-surgery lead to a higher rate of complications or re-occlusion following invasive therapy in comparison to male patients. A special anatomic manifestation appearing nearly only in women around the 6th decade ...

Yoga for Generalized Anxiety Disorder: Design of a Randomized Controlled Clinical Trial.

Generalized anxiety disorder (GAD) is a common disorder associated with significant distress and interference. Although cognitive behavioral therapy (CBT) has been shown to the most effective form of psychotherapy, few patients receive or have access to this intervention. Yoga therapy offers another promising, yet under-researched, intervention that is gaining increasing popularity in the general public, as an anxiety reduction intervention. The purpose of this innovative clinical trial protocol is to inves...

Yes, India has done it: Decriminalization of suicide in India.

Yeast Kluyveromyces lactis as host for expression of the bacterial lipase: cloning and adaptation of the new lipase gene from Serratia sp.

Many microbial lipases have been successfully expressed in yeasts, but not in industrially attractive Kluyveromyces lactis, which among other benefits can be cultivated on a medium supplemented with whey--cheap and easily available industrial waste. A new bacterial lipase from Serratia sp. was isolated and for the first time expressed into the yeast Kluyveromyces lactis by heterologous protein expression system based on a strong promoter of Kluyveromyces marxianus triosephosphate isomerase gene and signal p...

Yes-associated protein (YAP) expression is involved in epithelial-mesenchymal transition in hepatocellular carcinoma.

To investigate biological impact of the downregulation of yes-associated protein (YAP) through RNA interference in the process of epithelial-mesenchymal transition in MHCC97H and MHCC97L.

Young French neurosurgeons: Working conditions and outlook.

Due to the increase in the number of French neurosurgeon residents the neurosurgical workforce is changing. The main objective of this survey was to assess working conditions and perspectives for young French neurosurgeons.

Young Physicians' Leadership Curriculum: A Novel Approach to Creating Future Physician Leaders and Health Policy Advocates.

Yohimbine reinstates extinguished 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) seeking in rats with prior exposure to chronic yohimbine.

Although exposure to acute stress has been shown to reinstate extinguished responding for a wide variety of drugs, no studies have investigated stress-induced reinstatement in animals with a history of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) self-administration. Thus, rats were trained to press a lever for MDMA (0.50mg/kg/infusion) in daily sessions, and lever pressing was subsequently extinguished in the absence of MDMA and conditioned cues (light and tone). We then tested the ability of acute yo...

YouTube as a potential training method for laparoscopic cholecystectomy.

The purpose of this study was to analyze the educational quality of laparoscopic cholecystectomy (LC) videos accessible on YouTube, one of the most important sources of internet-based medical information.

You Down With ETC? Yeah, You Know D!

Although the mitochondrial electron transport chain (ETC) is best known for its role in ATP synthesis, two studies, Sullivan et al. and Birsoy et al., conclude that its only essential function in proliferating cells is making aspartate (D).

Yet another "disconnect" between amyloid and Alzheimer disease?

Yap control of tissue growth relies on cell density and F-actin in zebrafish fin regeneration.

Caudal fin regeneration is characterized by a proliferation boost in the mesenchymal blastema controlled precisely in time and space. This allows a gradual and robust restoration of original fin size. However, how this is established and regulated is not well understood. Here we report that Yap, the Hippo pathway effector, is a chief player in this process: functionally manipulating Yap during regeneration dramatically affects cell proliferation and expression of key signaling pathways, impacting regenerati...

Yap and Taz regulate retinal pigment epithelial cell fate.

During ocular morphogenesis the retinal pigment epithelium (RPE) and neural retina segregate fates from a bi-potential progenitor pool of cells comprising the optic vesicle. Several transcription factors and signaling pathways have been shown to be important for RPE maintenance and differentiation, but an understanding of the initial fate specification and determination of this ocular cell type is lacking. We show that Yap/Taz-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt ...

Yunnan Minority Eye Study Suggests That Ethnic Differences in Myopia Are Due to Different Environmental Exposures.