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PubMed Journal Database - Page: 2 RSS

21:21 EDT 30th July 2014 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 26–50 of 900

1033847

Yanagihara Facial Nerve Grading System as a Prognostic Tool in Bell's Palsy.

The aim of this study was to evaluate the accuracy of the Yanagihara facial nerve grading system in assessing the course of recovery and in determining the probability of a complete recovery of Bell's palsy within 1 week after onset.

1031549

Yellowing and bleaching of grey hair caused by photo and thermal degradation.

Yellowing is an undesirable phenomenon that is common in people with white and grey hair. Because white hair has no melanin, the pigment responsible for hair colour, the effects of photodegradation are more visible in this type of hair. The origin of yellowing and its relation to photodegradation processes are not properly established, and many questions remain open in this field. In this work, the photodegradation of grey hair was investigated as a function of the wavelength of incident radiation, and its...

1030942

Yeast cell lysis enhances dimethyl trisulfide formation in sake.

The present study showed that the lysis of yeast cells and subsequent release of cell contents in sake mash accelerated dimethyl trisulfide (DMTS) formation. Among these, heat unstable and relatively high molecular weight compounds were assumed to be enzymes; thus, enzymatic reactions probably contribute to DMTS formation.

1030448

You Keep Using That Term.

Monday 22nd August 1030

Yielding to Desire: The Durability of Affective Preferences.

People's expectations about the future are guided not just by the contingencies of situations but also by what they hope or wish will happen next. These preferences can inform predictions that run counter to what should or must occur based on the logic of unfolding events. Effects of this type have been regularly identified in studies of judgment and decision making, with individuals' choices often reflecting emotional rather than rational influences. Encouraging individuals to rely less on their emotional...

1029493

Yes! Sex Matters: Sex, the Brain and Blood Pressure.

The role of the brain in hypertension between the sexes is known to be important especially with regards to the effects of circulating sex hormones. A number of different brain regions important for regulation of sympathetic outflow and blood pressure express estrogen receptors (ERα and ERβ). Estradiol, acting predominantly via the ERα, inhibits angiotensin II activation of the area postrema and subfornical organ neurons and inhibits reactive oxygen generation that is required for the development of Angi...

Saturday 11th January 1028

Younger age at the time of first metastasis in BRAF-mutated compared to BRAF wild-type melanoma patients.

The relationship between BRAF mutations and the patient clinical profile is still under question. The objective of the present study was to correlate the BRAF mutation status in primary and metastatic melanomas with the clinicopathological profile, disease-free (DFS) and overall survival (OS). A total of 367 melanoma samples from 278 patients were screened for their BRAF status using a combination of allele-specific amplification and DNA sequencing. Two or three tissue samples from the same patient were ava...

1027785

Yellow/orange emissive heavy-metal complexes as phosphors in monochromatic and white organic light-emitting devices.

Owing to the electron spin-orbit coupling (SOC) and fast intersystem crossing (ISC), heavy-metal complexes (such as iridium(iii), platinum(ii) and osmium(ii) complexes, etc.) are phosphorescent emitters at room temperature. Since 1998, heavy-metal complexes as phosphors have received considerable academic and industrial attention in the field of organic light-emitting diodes (OLEDs), because they can harvest both the singlet (25%) and triplet (75%) excitons for emission during the electro-generated processe...

Monday 18th March 1027

Ytterbium-doped large-mode-area silica fiber fabricated by using chelate precursor doping technique.

We reported on a highly effective chelate precursor doping technique for Yb-doped large-mode-area (LMA) fiber manufacture. By accurately controlling the evaporation temperature and flow rate of carrier gas, the chelate precursor doping technique is capable of making Yb-doped LMA silica fiber with good uniformity free of center dip, low numerical aperture of ∼0.056, large preform core size of 4.46 mm, and appropriate cladding absorption of 1.17  dB/m at 976.4 nm. Based on a single-end-pump all-fiber...

1026749

You are what you eat: Gut microbiota determines kin recognition in Drosophila.

Gut bacteria is now considered as an additional host organ, and it has been shown that they have important influences on host developmental and physiological processes. More recently gut bacteria have additionally been implicated in behavioral processes. We showed that in two species of Drosophila, gut bacteria variation affects behavior, altering partner investment in copulation in relation to whether individuals were familiar (i.e., having developed in the same environment), or were related. This suggests...

1026495

YIA1 Early Detection of the Process of Vascular Calcification with Spect-ct and Pet-ct using Novel Bone Seeking Radiopharmaceuticals in Rat Models.

Vascular calcification is considered to be a significant predictor of coronary heart disease. It is also associated with serious clinical complications such as left ventricular hypertrophy and calcific uremic arteriolopathy. Matrix vesicles and apoptotic bodies (AB's) released by calcifying vascular smooth muscle cells (VSMC's) form the nidus for calcification in the vessel wall. Electron beam computed tomography (EBCT), the gold standard for non-invasive imaging and quantitation of vascular calcification f...

1026494

YIA2 PMCA1 Deletion Leads to Increased Blood Pressure and Cardiac Hypertrophy.

Heart failure is the common and final end point of cardiovascular disease. Seventy four percent of congestive heart failure patients also suffer from hypertension. Genome wide association studies (GWAS) have recently identified mutations in the ATP2B1 gene as having a strong association with hypertension risk. The ATP2B1 gene encodes the calcium extrusion pump, plasma membrane calcium ATPase (PMCA1), which also functions as a signalling molecule. This project aims to examine the link between PMCA1 and blood...

1026493

YIA4 Genetic Risk Markers for Atrial Fibrillation Influence Allelic Expression of Nearby Candidate Genes.

: Genome-wide association studies (GWAS) have identified genetic variants in nine chromosomal regions that are associated with atrial fibrillation (AF). The mechanisms underlying these associations are unknown. To investigate these mechanisms, we mapped associations between single nucleotide polymorphisms (SNPs) and allelic expression of candidate genes in the region of interest.

1026492

YIA5 RGS-1 Regulates Leukocyte Trafficking in Atherosclerosis and Aortic Aneurysm Formation through Chemokine Receptor Desensitisation.

: The regulation of macrophage recruitment and retention into the vascular wall is critical in the progression of atherosclerosis and aortic aneurysm formation. This can be mediated by chemokine activation of multiple G-protein coupled receptors. The Regulator of G-Protein Signalling-1 (RGS-1) acts to deactivate the intracellular response to sustained chemokine stimulation. We have found that RGS-1 is up-regulated with atherosclerotic plaque progression and with monocyte-macrophage activation. However littl...

Friday 13th April 1026

Yolk Sac Mesenchymal Progenitor Cells from New World Mice (Necromys lasiurus) with Multipotent Differential Potential.

Fetal membranes are abundant, ethically acceptable and readily accessible sources of stem cells. In particular, the yolk sac is a source of cell lineages that do not express MHCs and are mainly free from immunological incompatibles when transferred to a recipient. Although data are available especially for hematopoietic stem cells in mice and human, whereas other cell types and species are dramatically underrepresented. Here we studied the nature and differentiation potential of yolk sac derived mesenchymal...

1025898

Youth Risk Behavior Surveillance - United States, 2013.

Problem: Priority health-risk behaviors contribute to the leading causes of morbidity and mortality among youth and adults. Population-based data on these behaviors at the national, state, and local levels can help monitor the effectiveness of public health interventions designed to protect and promote the health of youth nationwide. Reporting Period Covered: September 2012-December 2013. Description of the System: The Youth Risk Behavior Surveillance System (YRBSS) monitors six categories of priority healt...

Tuesday 28th March 1025

Youth marijuana use: state of the science for the practicing clinician.

Despite widespread marijuana use among adolescents, accurate information on known health effects is poorly disseminated to clinicians and their patients. Amidst rapidly evolving drug policy in the United States and elsewhere, it is imperative that providers understand the short-term and long-term consequences of marijuana use.

1024564

Yacon (Smallanthus Sonchifolius): a food with multiple functions.

Abstract Functional foods are the focus of many studies worldwide. This is justified by the effects they have on public health and thus interest in elucidation of the mechanisms involved in their actions. The present review aims to broaden the discussions of the functional properties attributed to yacon (Smallanthus sonchifolius), considered a food with multiple functions since it possesses bioactive compounds (antimicrobial, antioxidant and probiotic substances) that exert beneficial effects on the body. A...

1023956

Young Children's Understanding of Denial.

Although a fair amount is known about young children's production of negation, little is known about their comprehension. Here, we focus on arguably the most complex basic form, denial, and how young children understand denial, when it is expressed in response to a question with gesture, single word, or sentence. One hundred twenty-six children in 3 age groups (Ms = 1 year 9 months, 2 years 0 months, and 2 years 4 months) witnessed an adult look into 1 of 2 buckets and then, in response to a question about...

1023804

Young Workers' Abilities to Self-report Agricultural Work Experience and Occupational Injuries Using Daily Diaries.

Tuesday 15th December 1023

Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis.

Organogenesis of the testis is initiated when expression of Sry in pre-Sertoli cells directs the gonad toward a male-specific fate. The cells in the early bipotential gonad undergo de novo organization to form testis cords that enclose germ cells inside tubules lined by epithelial Sertoli cells. Although Sertoli cells are a driving force in the de novo formation of testis cords, recent studies in mouse showed that reorganization of the vasculature and of interstitial cells also play critical roles in testis...

Thursday 30th April 1023

Youth varicocele and varicocele treatment: a meta-analysis of semen outcomes.

To study youth who have a varicocele or are undergoing varicocele treatment, in relation to changes in semen, as measured by semen analysis (SA).

1022903

Yeast Two-Hybrid System for Dissecting the Rice MAPK Interactome.

Protein-protein interactions are a preliminary but fundamental key to many biological systems. Identification of proteins that interact with particular bait not only contributes to a deeper understanding of bait protein function but also provides much information for the discovery of larger-scale interaction networks (interactome). Therefore, protein-protein interaction mapping is regarded as a widely accepted standardized functional genomics technique that provides comprehensive functional interpretation o...

Saturday 20th September 1022

Yeast phospholipid biosynthesis is linked to mRNA localization.

Localization of mRNAs and local translation are universal features in eukaryotes and contribute to cellular asymmetry and differentiation. In Saccharomyces cerevisiae, localization of mRNAs that encode membrane proteins requires the She protein machinery including the RNA-binding protein She2p as well as movement of the cortical endoplasmic reticulum (cER) to the yeast bud. In a screen for ER-specific proteins necessary for directional transport of WSC2 and EAR1 mRNAs, we have identified enzymes of the phos...

Sunday 27th October 1021

Yellow micropulse laser in diabetic macular edema: a short-term pilot study.

To evaluate the effects of yellow micropulse laser in eyes with diabetic macular edema (DME).


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