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05:37 EDT 18th September 2014 | BioPortfolio

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Showing PubMed Articles 1–25 of 78 from Fortschritte der Neurologie-Psychiatrie


Delirium and Dementia.


Delirium and Dementia.

Delirium and dementia as organically caused mental disorders exhibit similarities in the clinical and neurological sense and often occur together. The existence of one appears to increase the risk for the development of the other. Although delirium is a very common disorder especially among the elderly, it is often not recognized. For the diagnosis of delirium, an exact family and case history including medication, clinical examination and determination of routine laboratory values are not infrequently nece...


The Relationship between Therapist's Competence and Adherence to Outcome in Cognitive-Behavioural Therapy - Results of a Metaanalysis.

By now psychotherapy research has provided sufficient evidence in favour of the efficacy of psychotherapy, especially of the cognitive behaviour therapy (CBT). Hence one can argue that psychotherapy truly "works". Nevertheless, the rationale for the efficacy and the underlying mechanisms have not yet been explored. Resolving this ambiguity by focusing on the active ingredients in CBT is the aim of our review. More precisely we have explored whether the therapist's competence or his/her adherence to the CBT ...


Electroconvulsive Therapy in Depression: Insights from fMRI, PET and SPECT Studies.

Electroconvulsive therapy (ECT) is the most potent and rapidly acting of all antidepressant treatments in major depressive disorder (MDD). Nuclear and functional magnetic (fMRI) brain imaging studies of ECT have substantially contributed to the neurobiological understanding of this treatment modality. Neuroimaging methods may also validate potential mechanisms of antidepressant action. Models of neural dysfunction in MDD suggest impaired modulation of activity within a cortico-limbic circuitry, along with a...


Quality Assurance in Outpatient Neurological Rehabilitation: Measuring the Effects of Rehabilitation with the Competency Rating Scale.

Background: So far, there are only few studies concerning the outcome of outpatient neurological rehabilitation in Germany. Considering the statutory obligations of quality assurance there is an urgent need of appropriate instruments to assess the rehabilitation outcome. The aim of this study was to assess the appropriateness of the Competency Rating Scale (CRS), which was used to measure rehabilitation outcome, and to collect data of the effects of outpatient neurological rehabilitation as a measure of reh...


New Psychotropic Drugs - "Legal Highs"

Friday 14th August 1051

Clinical neuropsychology: at the crossroads or beyond?

Thursday 13th August 1051

Multiple Sclerosis, Neuromyelitis Optica and Spasticity: Control of Specific Symptoms and Quality of Life.

Spastic movement disorders show a high lifetime prevalence among patients suffering from multiple sclerosis and neuromyelitis optica. Due to the high number of factors interacting with the individual manifestations of spasticity, its symptomatic treatment affords continuous and careful balancing of therapeutic measures. A trend observed over the past few years is to base symptomatic treatment of MS on subjective assessments of functional disorders rather than on specific individual pathological signs and sy...

Wednesday 12th August 1051

Executive Task Performance under Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease Revisited: The Modulating Influence of Apathy, Depression and Mood.

We investigated the moderating influence of apathy, depression and transient mood changes on executive functions under best medical treatment and under postoperative stimulation-on and -off conditions in a sample of 33 patients with Parkinson's disease (PD) after deep brain stimulation of the subthalamic nucleus (STN), 33 PD patients with pharmacological treatment only and 34 healthy controls. In comparison to clinical and healthy control groups, DBS patients showed worse executive task performance and also...

Tuesday 11th August 1051

Indicators of Patient Care in Psychiatric and Psychosomatic Facilities (VIPP Project) - A Database Project.

Introduction: In Germany a new and unique remuneration system for psychiatric and psychosomatic stationary treatments (PEPP system) was introduced in 2013 on an optional basis. From 2015 it will be mandatory for psychiatric and psychosomatic facilities. The introduction of the PEPP system brings up different questions regarding the possible incentives of the new remuneration system and its effects on the supply of psychiatric and psychosomatic treatments. To conduct these necessary analyses a reliable datab...

Monday 10th August 1051

The "Erlangen System" of Open Care: A Tribute to Gustav Kolb (1870-1938).

Background: This year marks the 80th anniversary of the forced retirement (1st March 1934) of Gustav Kolb (1870 - 1938). He is considered the founder of the "Erlangen System" of open care. The following article pays tribute to Gustav Kolb's "life's work", by delineating the formation, active period and the fall of his "Erlangen system" in its historical context. Method: Relevant archive materials and secondary literature were assessed. Results: Beginning in 1914, Gustav Kolb, as Director of the Mental A...

Sunday 9th August 1051

Mortality and Sudden Unexpected Death in Epilepsy (SUDEP).

Thursday 12th July 1020

What should we eat?

Wednesday 11th July 1020

Glucocorticoids in Neurology: Mechanism of Action, Applications and Side Effects.

Glucocorticoids represent a cornerstone in the therapy for many neurological disorders. Even though their mechanism of action is still not completely understood, synthetic glucocorticoids are given as first line drugs in a number of immunological and non-immunological disorders of the central or peripheral nervous system. For most of these disorders, however, the level of evidence that glucocorticoids are truly effective is still not sufficient. This is why treatment with glucocorticoids cannot be recommend...

Tuesday 10th July 1020

Satellite Systems of the Basal Ganglia - Anatomic Position, Clinical Relevance.

The interaction of basal ganglia and other brain regions is more complex regarding anatomic and functional perspectives than previously assumed. Hence, the classical basal ganglia model has to be extended to at least four satellite systems modulating motor-executive, associative and limbic-motivational brain regions: (i) an indirect projection system, (ii) a striato-nigro-striatal loop, (iii) a "hyperdirect" projection system as well as additional projections to the subthalamic nucleus and (iv) multisynapti...

Monday 9th July 1020

Animal Hoarding: A Mental Disorder with Implications for Public Health.

Animal hoarding (AH) is a mental disorder that is characterised by an excessive number of kept animals, inability to maintain minimal standards of animal care and hygiene, and deficient insight into the thereby developing failures and problems. Although AH as a disease concept is neither represented in the DSM-5 nor the ICD-10, it may be classified as a subform of the hoarding disorder (DSM-5 300.3) that was implemented in the DSM-5 as an obsessive-compulsive disorder. Due to the hygienic deficiencies of t...

Sunday 8th July 1020

Adult ADHD versus Borderline Personality Disorder: Criteria for Differential Diagnosis.

The present study focuses on selected symptom criteria to distinguish between attention deficit/hyperactivity disorder (ADHD) in adults and borderline personality disorder (BPD). A sample of n = 158 subjects was examined, consisting of BPD patients (n = 37), ADHD patients (n = 58), comorbid BPD/ADHD patients (n = 19), a clinical group of patients fulfilling the diagnostic criteria of a depressive disorder (DEP; n = 22) and a non-clinical control group (KG; n = 22). Selected symptom c...

Saturday 7th July 1020

Long-term Treatment of Bipolar Disorder.


In Process Citation.


Neurobiology of attention deficit hyperactivity disorder.

The origin of ADHD is multifactorial and both the aetiology and pathophysiology of ADHD are as yet incompletely understood. The monoamine deficit hypothesis of ADHD postulates a dysbalance in the interaction of the neurotransmitters dopamine, noradrenaline and serotonin. Pathophysiological mechanisms involved in ADHD include alterations in fronto-striatal circuits. The currently proposed animal models of ADHD are heterogeneous with regard to their pathophysiological alterations and their ability to mimic be...


The new reimbursement for psychiatry and psychosomatics - challenges, opportunities and risks of the new financing system.

With the implementation of § 17 d KHG which provides for the introduction of a new, much more performance-based and transparent reimbursement system for psychiatric and psychosomatic hospitals, the Federal Ministry of Health sends the psychiatric and psychosomatic facilities in Germany into a previously unexplored area. Since 2013, there is the possibility of voluntary participation in the new system. Valid from 2015, every other institution will have to deal with the new challenges, opportunities and ...


Botulinum Toxin Injections for Chronic Migraine in Adolescents - An Early Therapeutic Option in the Transition from Neuropaediatrics to Neurology.

Background: The prevalence of chronic headaches in children and adolescents is up to 2 % resulting in the beginning of the later typical headache careers of adults. The therapy for chronic migraine with botulinum toxin is now established in adults. However, there is only limited experience in the use of botulinum toxin in paediatric patients. Methods: 10 patients aged 13 - 17 years who suffered from chronic migraine according to the IHS criteria were injected at 31 specific injection points of the hea...


Work rehabilitation for people with severe mental illness.


78% of stroke patients treated on 534 stroke units - (still?) fiction!.


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