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PubMed Journal Database | Fortschritte der Neurologie-Psychiatrie RSS

09:11 EDT 24th April 2014 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

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Showing PubMed Articles 1–25 of 60 from Fortschritte der Neurologie-Psychiatrie


In Process Citation.


Neurobiology of attention deficit hyperactivity disorder.

The origin of ADHD is multifactorial and both the aetiology and pathophysiology of ADHD are as yet incompletely understood. The monoamine deficit hypothesis of ADHD postulates a dysbalance in the interaction of the neurotransmitters dopamine, noradrenaline and serotonin. Pathophysiological mechanisms involved in ADHD include alterations in fronto-striatal circuits. The currently proposed animal models of ADHD are heterogeneous with regard to their pathophysiological alterations and their ability to mimic be...


The new reimbursement for psychiatry and psychosomatics - challenges, opportunities and risks of the new financing system.

With the implementation of § 17 d KHG which provides for the introduction of a new, much more performance-based and transparent reimbursement system for psychiatric and psychosomatic hospitals, the Federal Ministry of Health sends the psychiatric and psychosomatic facilities in Germany into a previously unexplored area. Since 2013, there is the possibility of voluntary participation in the new system. Valid from 2015, every other institution will have to deal with the new challenges, opportunities and...


Botulinum Toxin Injections for Chronic Migraine in Adolescents - An Early Therapeutic Option in the Transition from Neuropaediatrics to Neurology.

Background: The prevalence of chronic headaches in children and adolescents is up to 2 % resulting in the beginning of the later typical headache careers of adults. The therapy for chronic migraine with botulinum toxin is now established in adults. However, there is only limited experience in the use of botulinum toxin in paediatric patients. Methods: 10 patients aged 13 - 17 years who suffered from chronic migraine according to the IHS criteria were injected at 31 specific injection points of the hea...


Work rehabilitation for people with severe mental illness.


78% of stroke patients treated on 534 stroke units - (still?) fiction!.



Support to pass away.


Legal Ramifications of Medical End-of-Life Decisions in Dementia - Orientational Certainty through the Latest Decisions of the German Supreme Court?.

Taking care of dying people is one of the most difficult obligations of the physician, especially if these patients are suffering from dementia and accordingly when their current capacity to consent is arguable. In this field, numerous ethical and forensic problems arise that have to be considered. Legal medical end-of-life decisions that potentially shorten life (Sterbehilfe) are divided into two categories: direct "Sterbehilfe" refers to stopping life-prolonging measures. Indirect "Sterbehilfe" describes...


Psychopathological differentiation of depressive syndromes.

The historical contributions of Kurt Schneider, Karl Leonhard, Hans-Jörg Weitbrecht and Hubertus Tellenbach provide different concepts for a psychopathological differentiation of depressive syndromes. The current diagnostic systems ICD-10 and DSM-5 also contain categories for a differentiated classification of depressive disorders that trace back to the above historical concepts. The extensive diagnostic concepts of "depressive episode" or "major depression", however, are mainly based on the severity of sy...


Psychopathy in childhood and adolescence.

Personality disorders manifest themselves in stable deviations of personality traits that especially arise in negative interactions with others. Those typical dysfunctional interactions can be observed particularly in dissocial and antisocial personality disorders: adults with severe forms of personality disorders often showed specific symptoms in childhood and adolescence. Clinical researchers therefore demand a respective diagnosis of childhood and adolescent psychopathy. There is an extensive body of res...


On the History of Obsessive Compulsive Disorders: Their Place in the Nosological Classifications up to the Beginning of the 20th Century.

Influenced by French psychiatry, the first German works on obsessive-compulsive phenomena were published in the second half of the 19th century. First they were seen as one form of the unitary psychosis, later they became involved in the dispute about the concept of paranoia. The first German definition, proposed by Carl Westphal in 1877 and of crucial importance in the conceptual history of obsessive disorders as an illness (OCD) ever since, stood in this tradition. Still the adequate nosological classific...


Drug safety in clinical practice - part 2: psychopharmacological treatment.


In Process Citation.



From therapy to prevention.


Mental Health of Children, Adolescents and Young Adults - Part 1: Prevalence, Illness Persistence, Adversities, Service use, Treatment Delay and Consequences.

Numerous birth-control studies, epidemiological studies, and observational studies have investigated mental health and health care in childhood, adolescence and early adulthood, including prevalence, age at onset, adversities, illness persistence, service use, treatment delay and course of illness. Moreover, the impact of the burden of illness, of deficits of present health care systems, and the efficacy and effectiveness of early intervention services on mental health were evaluated. According to these da...


Mental health of children, adolescents and young adults - part 2: burden of illness, deficits of the german health care system and efficacy and effectiveness of early intervention services.

Numerous birth-control studies, epidemiological studies, and observational studies investigated mental health and health care in childhood, adolescence and early adulthood, including prevalence, age at onset, adversities, illness persistence, service use, treatment delay and course of illness. Moreover, the impact of the burden of illness, of deficits of present health care systems, and the efficacy and effectiveness of early intervention services on mental health were evaluated. According to these data, mo...


Cognitive deficits and dementia in patients with multiple sclerosis: status quo and open questions.

Multiple sclerosis (MS) is the most common chronic immune-mediated disease which goes along with serious somatic and psychic symptoms. Whereas recent research rather focussed on the neurological symptoms of MS, there is nowadays an increasing interest among researchers in psychological symptoms of the disease. It is known that about half of the MS patients suffer from cognitive deficits, and that cognitive decline has a disadvantageous impact on lifestyle and quality of life in affected persons. So far, cog...


DSM-5 - What has Changed in Therapy for and Research on Substance-Related and Addictive Disorders?.

The new edition of the DSM, which was published in May of 2013, has brought the following changes in the now called category "substance-related and addictive disorders". The terms dependency and misuse or abuse will be replaced by the terminus "substance use disorder". There is a moderate substance use disorder, if two or three criterias are fulfilled for a period of 12 months. To speak of a severe substance use disorder, it has to be four or more criteria for the duration of 12 months. Furthermore, patholo...


Long-term treatment of alcoholism.


In Process Citation.


Participation and its Measurement.


Repetitive Transcranial Magnetic Stimulation (rTMS) for Anxiety Disorders - A Possible Therapeutic Option?

Anxiety disorders rank among the most frequent psychiatric disorders. Effective psychotherapeutic and psychopharmacological interventions exist, although a considerable number of patients does not respond to standard interventions. Repetitive transcranial magnetic stimulation (rTMS) is capable of modulating cortical activity locally and non-invasively. Therefore, rTMS is discussed as a possible alternative treatment approach in psychiatric disorders. The present paper aims to provide a systematic review of...


Sleep Disturbances and Suicidality: Relationships and Clinical Implications.

Besides several risk factors for suicide, there is a recent increase in clinical and epidemiological studies pointing to a potential relationship between sleep loss or sleep disturbances and suicidality. This work, based on a systematic literature research, gives an overview on the findings of relationships between suicidality (i. e., suicidal thoughts, suicide attempts, suicides) and sleep disturbances, especially insomnia, nightmares, but also hypersomnia and nocturnal panic attacks. There is evidence tha...

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