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PubMed Journal Database | Fortschritte der Neurologie-Psychiatrie RSS

04:48 EST 8th December 2016 | BioPortfolio

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Showing PubMed Articles 1–25 of 195 from Fortschritte der Neurologie-Psychiatrie

Psychiatry Between Neurosciences and Social Sciences.

A Short Summary of the Psychopathological Construct by Karl Leonhard.

The so-called psychopathology according to Karl Leonhard is increasingly forgotten - similar to many other historical attempts to conceptualise psychiatric disorder. Therefore, this overview summarises briefly the principles of its construction. This may serve as the basis of future critical analyses in which then also the reasons for the fundamental failure of this approach may be discussed.

Repetitive Transcranial Magnetic Stimulation (rTMS) as a Therapeutic Tool in Psychiatry - Current State of Application in Germany.

The repetitive transcranial magnetic stimulation (TMS) opens new therapeutic options in neuropsychiatric disorders. The use of rTMS in depressive disorders has been most preferably investigated in clinical trials. In Germany, the application of rTMS outside of clinical trials is already increasingly common, not only for depression. Our nationwide survey in psychiatric hospitals was used to detect the current state of the application of rTMS in clinical practice, and should serve as a basis for the developme...

Treatment and Recidivism of Patients Convicted for Homicide After Release From a Forensic Psychiatry for Addiction Treatment.

The forensic clinic for addiction treatment in Rostock is a forensic institution for patients who committed crimes under the influence of psychotropic substances. Regardless of the severity of the offence, patients receive different kinds of treatment depending on the therapy program. Criminal recidivism can be seen as one of the most important factors to validate success in treatment. Due to this purpose, an extensive recidivism study including all former patients from 2001 to 2012 was conducted at our c...

On Criteria Diversity in Diagnostics of Adult Attention-Deficit/Hyperactivity Disorder.

The diagnosis of adult attention-deficit/hyperactivity disorder (ADHD) requires evidence for a persistence of core symptoms of the disorder since childhood, the differential diagnostic assessment of other psychiatric or neurologic disorders that might have elicited the current symptoms, an assessment of symptom relevance in terms of clinical impairment, as well as a survey of comorbid psychiatric disorders. Methods used within the diagnostic procedure are clinical questionnaires and interviews, personality ...

Insomnia Between Neuro- and Social Sciences - A Psycho-Socio-Somatic Outview.

Insomnia is one of the most prevalent neuropsychiatric disorders throughout Europe. It is associated with a number of health-relevant problems including an increased risk of psychiatric and organic disorders. A variety of organic, social and psychological risk factors takes part in the genesis of these sleep disturbances. A key component of the pathophysiology is the multifaceted hyperarousal that is expressed in the cognitive, emotional, neuronal, neuroendocrine, the hypothalamo-pituitary-adrenal axis, and...

The Role of Circadian Rhythms in Aging and ADHD.

The circadian rhythms coordinates the internal physiology to increase the homeostatic capacity thereby providing both a survival advantage to the system and an optimization of energy budgeting. Because multiple-oscillator circadian mechanisms are likely to play a role in regulating human health, and may contribute to the aging process, we give an overview of the relationship between the central clock in the hypothalamus and peripheral clocks for psychological health and aging.

Unexpected Complications in the Withdrawal Treatment of the Research Chemical AH-7921.

We describe the case of a young male patient who had consumed the morphine-like substance AH-7921 which is available via the internet. He was initially admitted to hospital because of obstipation and presented within a day of inpatient treatment for the first time with a generalized tonic-clonic epileptic seizure with subsequent urinary retention. Within a few hours, the patient then also developed bradycardia, while at the same time describing symptoms of physical opioid withdrawal which gradually deterior...

Autoimmune-Mediated Encephalomyelitis: a Heterogeneous Entity in Between Neurology and Psychiatry.

Within the last decade, autoantibody-associated encephalitis and encephalomyelitis have stepped into the focus of clinical research and practice. Besides the "classic" autoantibodies against intracellular neuronal antigenes, a growing number of antibodies directed against pre- and postsynaptic surface proteins of neurons have been described since the millennium change. Whereas the "classic" are closely linked to paraneoplastic syndromes, this association is loose for most of the yet known surface antigen-a...

Diagnostic Workup and Treatment of Antibody-Related Encephalomyelitis.

The results of laboratory tests for antineuronal antibodies in immune-mediated encephalitis nowadays are not only relevant for diagnostic purposes but are instead closely connected to outcome measures and treatment response. Besides the mere detection of antibodies, investigating the cerebrospinal fluid is indispensible to rule out an infectious etiology of encephalitis prior to the initiation of immunosuppressive treatment, whereas imaging studies are relevant to gain information on the temporal course of ...

Milestones of Child Neuropsychiatry.

The development of child and adolescent psychiatry took different pathways in East and West Germany after World War II. In East Germany, child and adolescent psychiatry put more emphasis on neurology as it was influenced by the foundation of the first chair and care unit in Rostock. Prof. Göllnitz, who held the chair for many years, established child and adolescent neuropsychiatry as a subject in its own right in research and health care and helped promoting it at other universities and medical academies.

Care Provided to Psychopaths in Rostock.

In the first decades of the 20(th) century stations for observing "psychopathological" children and adolescents were established at a number of psychiatric facilities in the German Reich. Often they functioned as the nucleus for future psychiatric clinics for children and adolescents. Using primary sources of the Landeshauptarchiv Schwerin (main land archive in Schwerin), the local development of the neuropsychiatric clinic in Rostock-Gehlsheim is illustrated in this paper, exploring the question to what de...

An Association Between Autonomy and National Ideology: The Founding of the Association for Psychiatry and Neurology in Mecklenburg.

Following the end of World War II, regional associations for psychiatry and neurology were founded in the Soviet Occupation Zone. Using the association in Mecklenburg as an example and considering the way society developed in the German Democratic Republic (GDR), it will be shown whether and to what degree these were increasingly subject to state control.

"Not suicidal": How valid is this clinical judgment?

Skin Diseases in Primary Psychiatric Disorders.

Somatic diseases in psychiatric disorders are frequently seen in clinical practice. Several international studies have shown that patients with a primary psychiatric disorder are at increased risk for developing severe somatic comorbidities in comparison to the normal population. Whereas there has been accumulation of knowledge on cardiovascular comorbidities, the relationship between skin and psychiatric disorders is less understood. There are only a few systematic studies on this subject and, in addition,...

Cognitive Development in Children with Benign Rolandic Epilepsy of Childhood with Centrotemporal Spikes - Results of a Current Systematic Database Search.

Benign Rolandic Epilepsy (BRE) is one of the most common epilepsy syndromes in childhood. Although global intellectual performance is typically normal in BRE-patients, problems were found in specific cognitive domains. To summarize recent empirical findings concerning cognitive development in children with BRE a systematic literature search of clinical studies published between 2009 and 2015 was performed. 19 studies of relevance were found.In most recent studies children with BRE consistently showed genera...

A New Diagnostic Tool for Apraxia in Patients with Right-Hemisphere Stroke: The Revised Cologne Apraxia Screening (KAS-R).

The Cologne Apraxia Screening (KAS) was developed to diagnose apraxia following left-hemisphere (LH) stroke. The present study aims at developing a diagnostic tool for patients with right-hemisphere (RH) stroke (KAS-R) by modifying the test material of the KAS and reducing the test items based on psychometric analyses.A total of 100 patients with RH stroke and 77 healthy control participants were tested. Psychometric analyses led to the exclusion of 8 KAS items. The final KAS-R, consisting of 12 items, show...

Ventilatory Support and Management of Secretions in Amyotrophic Lateral Sclerosis.

The term amyotrophic lateral sclerosis (ALS) comprises a group of motor neuron diseases which are characterized by rapid disease progression and poor prognosis which is mostly due to severe respiratory muscle weakness and its sequelae. Since causative treatment options are limited it is crucial to offer comprehensive symptomatic therapies to affect patients. Symptoms of respiratory muscle weakness, sleep-disordered breathing and, subsequently, chronic hypercapnic respiratory failure are known to severely af...

Psychopathological Differentiation of Psychotic Symptoms.

Assessing Motor-Cognition Interaction of Patients with Cognitive Disorders: Clinical Aspects.

Background: Difficulties of walking and deficits of cognitive functions appear to be associated in the elderly. Thus, clinical assessment in geriatry and neurology should focus on: (1) diagnostic approaches covering both domains of everyday functioning; (2) therapeutic interventions that take into account possible interactions and synergies of both domains. Discussion: In order to assess the capability for motor-cognitive interactions in the elderly it is recommended to investigate walking patterns during d...

The Concept of Typology in Psychiatry in the Context of Historical Contributions of Max Weber and Karl Jaspers.

Against the background of Max Weber's and Karl Jaspers' outstanding historical contributions to the conceptual development of different typologies, the importance of a psychiatric typology is examined. The term "ideal type" was introduced into social science by Weber as an analytical construct to describe and classify cultural phenomena. This concept was adopted for the psychiatric context by Jaspers who proposed to establish a typological system in the field of psychotic disturbances without an organic cor...

Factors Influencing Lead Time in Multiple Sclerosis: Survey of Members of the German Multiple Sclerosis Society in Saxony-Anhalt.

Background: Multiple sclerosis is a neurodegenerative disease of the central nervous system in which the myelin layer is disrupted. Early diagnosis and early therapy are decisive for the course of the disease. Methods: To analyze the time to diagnosis and the factors having an influence on this process, members of the German Multiple Sclerosis Society in Saxony-Anhalt (n = 941) were surveyed. Thanks to a return rate of 424 questionnaires (response rate ≈45 %), the results provide a good overview of ...

A Pair of Siblings with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis and a Novel Thr462Lysfs Mutation in the TBK1 Gene.

We report on a pair of siblings with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) and a novel Thr462Lysfs mutation in the TANK-binding kinase 1 (TBK1) gene identified through the European Early-Onset Dementia Consortium. The patients presented at the age of 77 and 75 years and displayed dementia and bulbar symptoms as well as progressive paresis. After a progressive course, both of them died only a few months after diagnosis. Most recently, TBK1 mutations were identified in patients...

Psychosis - clinical differential diagnosis.

Background: Many patients with psychiatric and organic disorders may present primary or secondary psychotic symptoms. Based on the ICD 10 classification, this article describes the possible underlying diseases and their subdivision. The main focus will be differential-diagnostic evaluations of psychotic syndromes. Results: In the clinical setting, the differential diagnosis of the paranoid schizophrenia and other psychotic disorders into three main disease groups is important: 1. other psychiatric diseases,...


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