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13:32 EDT 5th July 2015 | BioPortfolio

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Showing "London 2012 Unveils Anti Doping Laboratory" PubMed Articles 1–25 of 14,000+

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East London Experience with Enteric Fever 2007-2012.

The clinical presentation and epidemiology for patients with enteric fever at two hospitals in East London during 2007-2012 is described with the aim to identify preventive opportunities and to reduce the cost of treatment.

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Electronic and electrochemical doping of graphene by surface adsorbates.

Many potential applications of graphene require its precise and controllable doping with charge carriers. Being a two-dimensional material graphene is extremely sensitive to surface adsorbates, so its electronic properties can be effectively modified by deposition of different atoms and molecules. In this paper, we review two mechanisms of graphene doping by surface adsorbates, namely electronic and electrochemical doping. Although, electronic doping has been extensively studied and discussed in the literat...

Cobalt chloride doping in racehorses: Concerns over a potentially lethal practice.

The quest for assay robustness across the life cycle of a bioanalytical method.

White has been an analytical chemist for 28 years, with a range of knowledge and experience across multiple disciplines including pharmaceuticals, foodstuffs, environmental and forensic analysis. Steve works within the regulated bioanalytical group at GSK supporting both preclinical and clinical bioanalysis. His responsibilities have included leadership of bioanalytical, dose formulation and sample management teams as well as assisting with the set up of the Anti-Doping Testing Laboratory for the London 201...

Laboratory surveillance of Streptococcus pneumoniae from invasive disease, Chile 2007-2012.

Background: 10-valent pneumococcal vaccine (PCV-10) was introduced in 2011 to the National Immunization Program in Chile. It was administered in 4 doses, but in 2012 it was modified to a 3 dose program. This article shows the results of the Laboratory Surveillance System for Streptococcus pneumoniae isolated of invasive disease from 2007 to 2012 and compares the incidence of invasive pneumococcal disease (IPD) by age groups in the prevaccinal (2007-2010) and postvaccinal period (2012). Methods: Descriptive ...

A call for policy guidance on psychometric testing in doping control in sport.

One of the fundamental challenges in anti-doping is identifying athletes who use, or are at risk of using, prohibited performance enhancing substances. The growing trend to employ a forensic approach to doping control aims to integrate information from social sciences (e.g., psychology of doping) into organised intelligence to protect clean sport. Beyond the foreseeable consequences of a positive identification as a doping user, this task is further complicated by the discrepancy between what constitutes a ...

Epilepsy and Autoimmunity in Pediatric Patients.

Our aim was to determine the presence and possible role of autoantibodies in epileptic patients with an undetermined etiology. Eighty epilepsy patients, who were referred to the Pediatric Neurology Department at Ankara University between November 2011 and April 2012, were enrolled in the study. Antinuclear antibodies (ANA), anticardiolipin IgG, antiphospholipid, antithyroid peroxidase, paraneoplastic, glutamic acid decarboxylase (GAD), and N-methyl-d-aspartate (NMDA) receptor antibodies were studied in our ...

The clinical performance of a chemiluminescent immunoassay in detecting anti-cardiolipin and anti-β2 glycoprotein I antibodies. A comparison with a homemade ELISA method.

Abstract Background: Fully automated chemiluminescence immunoassays (CLIAs) are emerging technologies for the detection of anti-cardiolipin (aCL) and anti-β2 glycoprotein I (anti-β2GPI) antibodies for anti-phospholipid syndrome (APS) classification, which is commonly based on an enzyme-linked immunosorbent assay (ELISA) test result. CLIA and a homemade ELISA were used in this study to detect these antibodies, and their performances were compared. Methods: Sera were collected from 104 patients with primary...

Report on HbA1c Proficiency Testing in Asia in 2012.

In 2010, the Japan Diabetes Society decided to introduce the National Glycohemoglobin Standardization Program (NGSP) values into clinical practice. Accordingly, NGSP Certification of Japanese manufacturers of HbA1c-related diagnostic reagents and instruments was initiated in February, 2012, through an NGSP network laboratory, the Asian Secondary Reference Laboratory (ASRL) #1. Traceability to the NGSP reference system can be endorsed by manufacturer certification, as well as by the College of American Patho...

The effect of implicitly incentivized faking on explicit and implicit measures of doping attitude: when athletes want to pretend an even more negative attitude to doping.

The Implicit Association Test (IAT) aims to measure participants' automatic evaluation of an attitude object and is useful especially for the measurement of attitudes related to socially sensitive subjects, e.g. doping in sports. Several studies indicate that IAT scores can be faked on instruction. But fully or semi-instructed research scenarios might not properly reflect what happens in more realistic situations, when participants secretly decide to try faking the test. The present study is the first to in...

Unlocking the functional properties in one-dimensional MoSI cluster polymers by doping and photo-induced charge transfer.

To improve functionalization of MoSI cluster polymers we have studied the effects of adsorption doping on the electrical transport, bundling, and optical absorption spectra. Doping results both in enhanced conductivity and aggregated bundles in dispersion. The different electronic properties of different bundle diameters can be ascribed to self-doping during the synthesis. Furthermore, doping shifts the characteristic absorption peaks and transfers oscillator strength to lower energies. Femtosecond optical ...

Medical laboratory quality systems - a management review.

Purpose - The purpose of this paper is to highlight changes in ISO 15189:2012 and ISO 15189:2007 concerning management review requirements and to present a management review checklist, which includes all the revised ISO 15189's requirements. Design/methodology/approach - The recent revised and updated ISO 15189:2012 standard recommends a management review using a process approach and includes some additional topics. Findings - The management review is a key element in many quality management systems, includ...

Tunable Dirac electron and hole self-doping of topological insulators induced by stacking defects.

Self-doping of Dirac cones in Bi2X3 (X=Se, Te) topological insulators can be tuned by controlling the sequence of stacking defects in the crystal. Twin boundaries inside Bi2X3 drive n- or p-type doping of the surface states, originated by the defect induced spontaneous polarization. Doping up to 10(12)-10(13) e/cm(2) may be achieved depending on the defect distribution. Our findings open the route to fabrication of Bi2X3 surfaces with tailored intrinsic charge and spin densities.

Anti-oxidant, anti-inflammatory and antinociceptive properties of the acetone leaf extract of vernonia amygdalina in some laboratory animals.

Vernonia amygdalina is a medicinal plant of great importance that has its fresh leaves rich in vitamins and salt hence, it is valuable in human diet. The anti-oxidant, anti-inflammatory and analgesic activities of its acetone leaf extract were evaluated in this study to validate its folkloric use.

The anomaly Cu doping effects on LiFeAs superconductors.

The Cu substitution effect on the superconductivity of LiFeAs has been studied in comparison with Co/Ni substitution. It is found that the shrinking rate of the lattice parameter c for Cu substitution is much smaller than that of Co/Ni substitution. This is in conjugation with the observation of ARPES that shows almost the same electron and hole Fermi surfaces (FSs) size for undoped and Cu substituted LiFeAs sample, except for a very small hole band sinking below Fermi level with doping. This indicates that...

Pertussis Outbreak, Southeastern Minnesota, 2012.

To describe clinical and laboratory findings from the 2012 southeastern Minnesota pertussis outbreak.

Doping of C70 fullerene peapods with lithium vapor: Raman spectroscopic and Raman spectroelectrochemical studies.

Raman spectroscopy and in situ Raman spectroelectrochemistry were applied to study the lithium vapor doping of C70@SWCNTs (peapods). A strong degree of doping was proved by the vanishing of the single walled carbon nanotubes (SWCNT's) radial breathing mode (RBM) and by the attenuation of the tangential (TG) band intensity. In contrast to potassium vapor doping, the strong downshift of the frequency of the TG band has not been observed for Li-doping. The Li vapor treated peapods remained partly doped even if...

Controlling the dopant dose in silicon by mixed monolayer doping.

Molecular monolayer doping (MLD) presents an alternative to achieve doping of silicon in a nondestructive way, and holds potential for realizing ultra-shallow junctions and doping of non-planar surfaces. Here, we report the mixing of dopant-containing alkenes with alkenes that lack this functionality, at various ratios to control the dopant concentration in the resulting monolayer and concomitantly the doping dose in the silicon substrate. The mixed monolayers were grafted onto hydrogen-terminated silicon u...

Wide-Range Controllable n-Doping of Molybdenum Disulfide (MoS2) through Thermal and Optical Activation.

Despite growing interest in doping two-dimensional (2D) transition metal dichalcogenides (TMDs) for future layered semiconductor devices, controllability is currently limited to only heavy doping (degenerate regime). This causes 2D materials to act as metallic layers, and an ion implantation technique with precise doping controllability is not available for these materials (e.g., MoS2, MoSe2, WS2, WSe2, graphene). Since adjustment of the electrical and optical properties of 2D materials is possible within a...

Functionalization of Transition Metal Dichalcogenides with Metallic Nanoparticles: Implications for Doping and Gas-Sensing.

Transition Metal Dichalcogenides (TMDs), belonging to the class of two-dimensional (2D) layered materials, have instigated a lot of interest in diverse application fields due to their unique electrical, mechanical, magnetic and optical properties. Tuning the electrical properties of TMDs through charge transfer or doping is necessary for various optoelectronic applications. This paper presents the experimental investigation of the doping effect on TMDs, mainly focusing on molybdenum disulphide (MoS2), by me...

Registered report: The CD47-signal regulated protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.

The Willingham et al., 2012, published in PNAS in 2012. The key experiments being replicated are those reported in Figure 6A-C and Table S4. In these experiments, Willingham et al., 2012 test the safety and efficacy of anti-CD47 antibody treatment in immune competent mice utilizing a syngeneic model of mammary tumor growth in FVB mice. The Reproducibility Project: Cancer Biology is a collaboration between the eLife.

Resolution properties of transmission-mode exponential-doping Ga0.37Al0.63As photocathodes.

Using the modulation transfer function obtained by establishing and solving the two-dimensional continuity equation, we have calculated and comparatively analyzed the resolution characteristics of transmission-mode exponential-doping and uniform-doping Ga0.37Al0.63As photocathodes. The calculations show that compared with a uniform-doping Ga0.37Al0.63As photocathode, the exponential-doping structure can significantly improve not only the resolution, but also the quantum efficiency of the photocathode. This ...

Dramatic decline in substance use by HIV-infected pregnant women in the United States from 1990 to 2012.

We aimed to describe temporal changes in substance use among HIV-infected pregnant women in the United States from 1990 to 2012.

Evaluation of Commercially Available Diagnostic Tests for the Detection of Dengue Virus NS1 Antigen and Anti-Dengue Virus IgM Antibody.

Commercially available diagnostic test kits for detection of dengue virus (DENV) non-structural protein 1 (NS1) and anti-DENV IgM were evaluated for their sensitivity and specificity and other performance characteristics by a diagnostic laboratory network developed by World Health Organization (WHO), the UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR) and the Pediatric Dengue Vaccine Initiative (PDVI). Each network laboratory contributed characterized serum ...

Chloride Molecular Doping Technique on 2D Materials: WS2 and MoS2.

Low-resistivity metal-semiconductor (M-S) contact is one of the urgent challenges in the research of 2D transition metal dichalcogenides (TMDs). Here, we report a chloride molecular doping technique which greatly reduces the contact resistance (Rc) in the few-layer WS2 and MoS2. After doping, the Rc of WS2 and MoS2 have been decreased to 0.7 kΩ•μm and 0.5 kΩ•μm, respectively. The significant reduction of the Rc is attributed to the achieved high electron doping density thus significant reduction of ...



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