Treatment of Naevus Flammeus Using Intense Pulsed Light and Pulsed Dye Laser
Summary
The purpose of the trial is to compare efficacy and adverse effects of pulsed dye laser and intense pulsed light in patients with port wine stains.
Study Design
Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind, Primary Purpose: Treatment
Conditions
Port-Wine Stain
Intervention
Pulsed dye laser (Candela), Intense pulsed light (Palomar)
Location
Bispebjerg Hospital
Copenhagen
Copenhagen nv
Denmark
2400
Status
Completed
Source
Bispebjerg Hospital
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00365118
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Lasers, Dye
Tunable liquid lasers with organic compounds (i.e., dye) which have a strong absorption band, used as the active medium. During emission, the dye has to be optically excited by another light source (e.g., another laser or flash lamp). The range of the emission wavelength may be anywhere from the ultraviolet to the near infrared (i.e., from 180 to 1100nm). These lasers are operated in continuous wave and pulsed modes. (UMDNS, 2005)
Light Coagulation
The coagulation of tissue by an intense beam of light, including laser (LASER COAGULATION). In the eye it is used in the treatment of retinal detachments, retinal holes, aneurysms, hemorrhages, and malignant and benign neoplasms. (Dictionary of Visual Science, 3d ed)
Lasers
An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.
Electrochemotherapy
A treatment modality that uses pulsed electrical currents to permeabilize cell membranes (ELECTROPORATION) and thereby enhance the uptake of chemotherapeutic agents, vaccines, or genes into the body's cells.
Molecular Typing
Using MOLECULAR BIOLOGY techniques, such as DNA SEQUENCE ANALYSIS; PULSED-FIELD GEL ELECTROPHORESIS; and DNA FINGERPRINTING, to identify, classify, and compare organisms and their subtypes.
Clinical Trials
Long-Pulsed Dye Laser and Intense Pulsed Light for Skin Rejuvenation.
The purpose of the trial is to compare clinical efficacy and occurrence of side effects in the treatment of photodamaged skin with Pulsed Dye Laser and Intense Pulsed Light.
Pulsed Dye Laser and Intense Pulsed Light (IPL) for the Treatment of Telangiectasia and Skin Redness
The purpose of the study is to compare efficacy and adverse effects of pulsed dye laser and intense pulsed light in patients with skin telangiectasia and redness.
Combined Photodynamic and Pulsed Dye Laser Treatment of Port Wine Stains
This research study was designed to determine the effect on port wine stains (PWS) of liposomal benzoporphyrin derivative monoacid (BPD-MA) termed verteporfin (distributed for medical indi...
Laser-Mediated Photodynamic Therapy of Acne Vulgaris and Rosacea
To evaluate efficacy and adverse effect from long-pulsed dye laser versus long-pulsed dye laser-mediated photodynamic therapy for acne vulgaris and rosacea.
The purpose of this study is to improve port wine stain (PWS) therapeutic outcome in response to pulsed dye laser (PDL) therapy by comparison of 577 nm versus 595 nm Wavelengths. Th...
PubMed Articles
Treatment of facial port-wine stains with a new intense pulsed light source in Chinese patients.
Abstract Background: Intense pulsed light (IPL) systems have been used for the treatment of port-wine stains (PWS) for more than 10 years. Some of them have been reported in the treatment of laser-res...
ABSTRACT Background: Hirsutism is a common disorder in women of reproductive age and androgen disturbances may aggravate the condition. Limited evidence exists regarding hair removal efficacy in this...
Objectives Acoustic cavitation can be fatal to cells and is used to destroy cancerous tumors. The particles in a liquid decrease the ultrasonic intensity threshold needed for onset of cavitation. Bubb...
Reflectance spectroscopy can be used to quantitate subtle differences in color. We applied a portable reflectance spectrometer to determine its utility in the evaluation of pulsed dye laser treatment...
Laser Treatment of Dyschromia With a Novel 607 nm Pulsed-Dye Laser.
Background: Due to the hemoglobin-selective wavelength of the 595 nm pulsed-dye laser, it is a device of choice for treating cutaneous vascular lesions. However, it is less effective and removing dysc...
