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Implantation of Porous Titanium Prosthesis in Laryngeal Surgery

04:45 EDT 29th July 2014 | BioPortfolio

Summary

This study evaluates a medialization implant to treat vocal cord paralysis, to permit it to adjust the quality of the voice under local or general anesthesia. The aim is to restore phonation using a porous titanium prosthesis in laryngeal surgery.

Study Design

Allocation: Non-Randomized, Control: Historical Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Vocal Cord Paralysis

Intervention

Vocal fold medialization (thyroplasty) prosthesis by insertion of a new implant allowing very easy and quick setting

Location

Service d'Oto-Rhino-Laryngologie et de Chirurgie Cervico-Faciale, Hôpital de Hautepierre
Strasbourg
France

Status

Not yet recruiting

Source

University Hospital, Strasbourg, France

Results (where available)

View Results

Links

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This phase I single center open labeled study is planned to assess the safety and tolerability of bevacizumab for treating patients with bilateral RRP. Approximately 20 patients will recei...

Reconstruction Implant Bone After Removal Using Porous Titanium Prosthesis

This trial will study the reconstruction of the anterior part of the mandible and the adjacent soft tissue parts by a mandibular prosthesis made in porous titanium, associated or not, to a...

Improving Functional Outcomes in Patients With Unilateral Vocal Cord Paralysis: Assessment of Adaptation Using Functional Magnetic Resonance Imaging

The purpose of this study is to see how the brain re-learns to control the larynx in speaking and swallowing when undergoing surgical rehabilitation in the form of either thyroplasty or vo...

Characteristics of Idiopathic Familial Voice Disorders

The purpose the study is to determine the genetic causes of specific voice disorders that run in families. Researchers are particularly interested in two conditions; 1. Spasmodic dysph...

Laser Treatment Of Vascular Lesions On Vocal Cords

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PubMed Articles [6118 Associated PubMed Articles listed on BioPortfolio]

Pre and post operative voice analysis after medialization thyroplasty in cases of unilateral vocal fold paralysis.

The present study was undertaken to assess the efficacy of medialization thyroplasty on outcome of voice quality in vocal cord paralysis by analyzing the voice. A total 19 patients with vocal cord par...

Use of the video-laryngoscope (GlideScope) in vocal fold injection medialization.

Diagnostic and therapeutic pitfalls in benign vocal fold diseases.

More than half of patients presenting with hoarseness show benign vocal fold changes. The clinician should be familiar with the anatomy, physiology and functional aspects of voice disorders and also t...

Favorable vocal fold wound healing induced by platelet-rich plasma injection.

To introduce a new injection material for vocal fold diseases, which could be readily translated to clinical practice, we investigated the effectiveness of platelet-rich plasma (PRP) injection on the...

Mechanical Regulation of Human Vocal Fold Stellate Cells.

It is generally accepted that tensile and compressive strains have direct effects on cell morphology and structure, including changes in cytoskeletal structure and organization. Cytoskeletons play the...

Medical and Biotech [MESH] Definitions

Insertion of an implant into the bone of the mandible or maxilla. The implant has an exposed head which protrudes through the mucosa and is a prosthodontic abutment.

Surgical insertion of a prosthesis.

A prosthesis that gains its support, stability, and retention from a substructure that is implanted under the soft tissues of the basal seat of the device and is in contact with bone. (From Boucher's Clinical Dental Terminology, 4th ed)

Surgical insertion of an appliance for the replacement of areas of the maxilla, mandible, and face. When only portions of the mandible are replaced, it is referred to as MANDIBULAR PROSTHESIS IMPLANTATION.

Surgical insertion of an implant to replace one or more of the ear ossicles.

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Anesthesiology
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An anesthesiologist (US English) or anaesthetist (British English) is a physician trained in anesthesia and perioperative medicine. Anesthesiologists are physicians who provide medical care to patients in a wide variety of (usually acute) situations....

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