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Antibiotic Prophylaxis in Open Fractures

2016-10-19 02:38:21 | BioPortfolio

Summary

Prospective look at antibiotic prophylaxis with Ceftaroline in patients with type II and III open fractures

Description

Determine if antibiotic prophylaxis with Ceftaroline in patients with type II and III open fractures is a safe and effective alternative to standard combination therapy

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Open Fractures

Intervention

Ceftaroline

Location

Triple O Research Institute PA
West Palm Beach
Florida
United States
33401

Status

Not yet recruiting

Source

Triple O Research Institute PA

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-10-19T02:38:21-0400

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PubMed Articles [4559 Associated PubMed Articles listed on BioPortfolio]

Management of Pediatric Type I Open Fractures in the Emergency Department or Operating Room: A Multicenter Perspective.

The management of pediatric type I open fractures remains controversial. The aim of this study is to compare outcomes in type I open fractures managed with superficial wound debridement and antibiotic...

Impact of Body Mass Index and Bacterial Resistance in Osteomyelitis after Antibiotic Prophylaxis of Open Lower-Extremity Fractures.

We investigated the clinical effectiveness of antimicrobial prophylaxis in lower-extremity open fractures following the Eastern Association for the Surgery of Trauma Guidelines.

Use of a defined surgical approach for the debridement of open tibia fractures.

To determine whether a defined approach for debridement of open tibia fractures would result in no change in reoperation rate, but reduce the need for flap coverage.

Cerclage-wiring through a mini-open approach to assist reduction of subtrochanteric fractures treated with cephalomedullary fixation: surgical technique.

In spite of advances in the management of subtrochanteric fractures, in particular the use of cephalomedullary nails, surgical results still remain poorer than other fractures of the proximal femur. G...

Factors of Pelvic Infection and Death in Patients with Open Pelvic Fractures and Rectal Injuries.

Open pelvic fractures associated with rectal injuries are uncommon. They often cause serious pelvic infection, even death. This combination of injuries has been reviewed infrequently. Herein, we repor...

Medical and Biotech [MESH] Definitions

Fractures in which there is an external wound communicating with the break of the bone.

Fractures of the short, constricted portion of the thigh bone between the femur head and the trochanters. It excludes intertrochanteric fractures which are HIP FRACTURES.

A skull fracture characterized by inward depression of a fragment or section of cranial bone, often compressing the underlying dura mater and brain. Depressed cranial fractures which feature open skin wounds that communicate with skull fragments are referred to as compound depressed skull fractures.

Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).

Fractures of the skull which may result from penetrating or nonpenetrating head injuries or rarely BONE DISEASES (see also FRACTURES, SPONTANEOUS). Skull fractures may be classified by location (e.g., SKULL FRACTURE, BASILAR), radiographic appearance (e.g., linear), or based upon cranial integrity (e.g., SKULL FRACTURE, DEPRESSED).

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