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Levofloxacin Triple and Bismuth Quadruple Therapies for Rescue Treatment of H Pylori Infection

2016-12-01 16:08:22 | BioPortfolio

Summary

From the profiles of antibiotic susceptibility data following eradication therapy, tetracycline, amoxicillin and levofloxacin are all good candidates of antibiotics used in the rescue treatment.

Description

The H pylori-infected adult patients with failure of standard triple therapy and H pylori-infected adult patients with failure of non-bismuth quadruple therapy are randomly assigned to either EAL (esomeprazole 40 mg b.d., amoxicillin 500 mg q.d.s., and levofloxacin 500 mg o.d.) or EBTL (esomeprazole 40 mg b.d., bismuth 500 mg q.d.s., tetracycline 500 mg q.d.s., and levofloxacin 500 mg o.d.) therapy for 10 days. Repeated endoscopy with rapid urease test, histological examination and culture or urea breath tests is performed at six weeks after the end of anti-H pylori therapy.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Helicobacter Pylori Infection

Intervention

esomeprazole+amox+levo, esomeprazole+bismuth+tetra+levo

Location

Kaohsiung Veterans General Hospital
Kaohsiung
Taiwan
813

Status

Recruiting

Source

Kaohsiung Veterans General Hospital.

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-12-01T16:08:22-0500

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