Search Results for "Didodecyldimethylammonium Bromide And Cancer"

01:29 EST 19th December 2014 | BioPortfolio

Original Source: Didodecyldimethylammonium bromide (DDAB) induces caspase-mediated apoptosis in human leukemia HL-60 cells.

Didodecyldimethylammonium bromide (DDAB) is widely used for an efficient delivery system into mammalian cells. However, the biological activities of DDAB nanoparticles in mammalian cells are insufficiently understood. The purpose of this study was to establish a critical role of DDAB in cellular response. Here, we demonstrate that DDAB is a potent inducer of cell death in a wide range of tumor cell lines, wherein leukemia cells (HL-60 and U937) and neuroblastoma cells (Neuro2a) were more sensitive to DDAB t...

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Methylnaltrexone bromide (Relistor) for opioid-induced constipation in adult patients with chronic non-malignant pain

Methylnaltrexone bromide (Relistor) is administered subcutaneously (SC) and intended for use as a first or subsequent line therapy for the treatment of opioid-induced constipation in adult patients wi...

Almirall’s aclidinium bromide/formoterol backed by EMA/CHMP to treat COPD

The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion for the regulatory approval of Duaklir Genuair (aclidinium bromide/formoterol fuma...

Almirall’s aclidinium bromide/formoterol fumarate recommended for approval in Europe to treat COPD

Almirall S.A. announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has issued a positive opinion for the regulatory approval of Duaklir® Genuair® (aclid...

FDA advisory committee recommends approval of Tiotropium Respimat COPD

The FDA Pulmonary-Allergy Drugs Advisory Committee (PADAC) voted (10 yes, three no) t/news-online/company/Boehringer+Ingelheimhat existing data supports approval of Boehringer Ingelheim's investigati...

Spiriva Respimat tiotropium bromide regulatory update

FDA approves Salix’s RELISTOR subcutaneous injection sNDA

Salix Pharmaceuticals and Progenics Pharmaceuticals have announced that the Food and Drug Administration (FDA or Agency) has informed Salix that RELISTOR (methylnaltrexone bromide) Subcutaneous Inject...

Umeclidinium bromide/fluticasone furoate/vilanterol: Phase III started

Aclidinium bromide/formoterol fumarate: Additional Phase III data

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Magnetically-responsive electrophoretic silica organosols.

Silica nanoparticles can be dispersed in organic solvents (organosols) using surfactants, such as didodecyldimethylammonium bromide (DDAB). DDAB analogs prepared with lathanide tetrahalide counterions...

High Cytotoxic Activity of Phosphonium Salts and Their Complementary Selectivity towards HeLa and K562 Cancer Cells: Identification of Tri-n-butyl-n-hexadecylphosphonium bromide as a Highly Potent Anti-HeLa Phosphonium Salt.

Quaternary ammonium and phosphonium salts have been screened for their toxic effect on HeLa and K562 cancer cell lines, as well as on normal HUVEC cells. Tri-n-butyl-n-hexadecylphosphonium bromide, th...

A critical evaluation of bioimpedance spectroscopy analysis in estimating body composition during GH treatment: comparison with bromide dilution and dual X-ray absorptiometry.

Objective: To compare estimates by Bioimpedance Spectroscopy Analysis (BIS) of extracellular water (ECW), fat mass (FM), and fat free mass (FFM) against standard techniques of bromide dilution and DXA...

Cytotoxic and apoptotic effects of synthetic benzochromene derivatives on human cancer cell lines.

With the aim of discovering potential cytotoxic agents, a series of benzochromene derivatives were screened for their cytotoxic activity against seven human cancer cell lines by standard 3-(4, 5-dimet...

The Selective Oxidation of Alcohols Using Alkali Metal Bromides as Bromide Catalysts: A Experimental Study of the Reaction Mechanism.

A bromide-catalyzed oxidation of alcohols was developed which proceeded in the presence of an alkali metal bromide and an oxidant under mild conditions. The reaction involved an organic-molecule-free ...

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