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19:59 EDT 28th May 2016 | BioPortfolio

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Improvised naloxone nasal sprays lack evidence of absorption and effect

Naloxone hydrochloride is a medication that can reverse the effects of an opioid overdose. First responders (peers, family, police, etc.) may prefer nasal sprays to injectable naloxone, which has led ...

Supine Delivery of OTC Oxymetazoline Nasal Drops Risks Serious Toxicity

One squeeze of 0.05% oxymetazoline nasal spray held at a 45° angle delivers a potentially toxic dose.

Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys

Being one of the most common nasal diseases, chronic rhinosinusitis (CRS) is subdivided into CRS with nasal polyps (NP) and CRS without nasal polyps (CRSsNP). CRSsNP presents itself with a TH1 milieu ...

Corticosteroid nasal spray delays treatment in patients with severe nasal obstruction

A mandatory use of corticosteroid nasal spray resulted in delay in treatment for patients with severe-to-extreme nasal obstruction, according to study results published in JAMA Facial Plastic Surgery....

Rhinoplasty effective treatment for nasal valve insufficiency

(HealthDay)—For patients with nasal valve insufficiency, functional and aesthetic-functional rhinoplasty, involving reconstruction of the lateral nasal wall achieved with use of spreader and alar gr...

Pharmaceutical Research: Absorption and Clearance of Pharmaceutical Aerosols in the Human Nose: Effects of Nasal Spray Suspension Particle Size and Properties

Type: Original PaperPurposeThe objective of this study was to use a recently developed nasal dissolution, absorption, and clearance (DAC) model to evaluate the extent to which suspended drug particle ...

Adapt Pharma’s Narcan Nasal Spray now available in U.S.

David SalazarThe nasal spray is an emergency treatment for opioid overdose, and the only naloxone nasal spray approved by the Food and Drug Administration in the United States, according to the compan...

Nasal Drug Delivery

7 - 8 April 2016, Conference, London, UK

Matching PubMed Articles

Cell-Penetrating Peptide Penetratin as a Potential Tool for Developing Effective Nasal Vaccination Systems.

Nasal vaccination is considered an attractive strategy to prevent the infection and spread of viruses. However, the vaccine formulations available on the market remain imperfect on account of their li...

Primary Air Liquid Interface Culture of Nasal Epithelium for Nasal Drug Delivery.

Nasal drug administration is a promising alternative to oral and parenteral administration for both local and systemic delivery of drugs. The benefits include its non-invasive nature, rapid absorption...

Mitek Suspension of the Lateral Nasal Wall.

The nasal valve has long been described as the anatomical boundary most likely to inhibit nasal airflow and lead to subsequent nasal obstruction. Although many procedures can address this area to impr...

A Novel Drug Delivery System for the Human Nasal Epithelium.

The epithelium of upper respiratory tissues such as the human nasal mucosa forms a continuous barrier via tight junctions (TJs). The development of a drug delivery system for use across the nasal muco...

Optimization of magnetophoretic-guided drug delivery to the olfactory region in a human nose model.

Magnetophoretic-guided delivery has been shown to be able to improve the olfactory doses. However, due to the complex nasal structure and quick decay of magnetic intensity, precise control of particle...

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