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06:29 EDT 5th May 2016 | BioPortfolio

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Improvised naloxone nasal sprays lack evidence of absorption and effect

Naloxone hydrochloride is a medication that can reverse the effects of an opioid overdose. First responders (peers, family, police, etc.) may prefer nasal sprays to injectable naloxone, which has led ...

Supine Delivery of OTC Oxymetazoline Nasal Drops Risks Serious Toxicity

One squeeze of 0.05% oxymetazoline nasal spray held at a 45° angle delivers a potentially toxic dose.

Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys

Being one of the most common nasal diseases, chronic rhinosinusitis (CRS) is subdivided into CRS with nasal polyps (NP) and CRS without nasal polyps (CRSsNP). CRSsNP presents itself with a TH1 milieu ...

Corticosteroid nasal spray delays treatment in patients with severe nasal obstruction

A mandatory use of corticosteroid nasal spray resulted in delay in treatment for patients with severe-to-extreme nasal obstruction, according to study results published in JAMA Facial Plastic Surgery....

Rhinoplasty effective treatment for nasal valve insufficiency

(HealthDay)—For patients with nasal valve insufficiency, functional and aesthetic-functional rhinoplasty, involving reconstruction of the lateral nasal wall achieved with use of spreader and alar gr...

Pharmaceutical Research: Absorption and Clearance of Pharmaceutical Aerosols in the Human Nose: Effects of Nasal Spray Suspension Particle Size and Properties

Type: Original PaperPurposeThe objective of this study was to use a recently developed nasal dissolution, absorption, and clearance (DAC) model to evaluate the extent to which suspended drug particle ...

Adapt Pharma’s Narcan Nasal Spray now available in U.S.

David SalazarThe nasal spray is an emergency treatment for opioid overdose, and the only naloxone nasal spray approved by the Food and Drug Administration in the United States, according to the compan...

Zicam launches zinc-free nasal swabs

Michael Johnsen The new formula Zicam Nasal Swab is homeopathic, zinc-free and provides cooling menthol and eucalyptus to help soothe the nasal passages upon application.   read more

Matching PubMed Articles

Mitek Suspension of the Lateral Nasal Wall.

The nasal valve has long been described as the anatomical boundary most likely to inhibit nasal airflow and lead to subsequent nasal obstruction. Although many procedures can address this area to impr...

A Novel Drug Delivery System for the Human Nasal Epithelium.

The epithelium of upper respiratory tissues such as the human nasal mucosa forms a continuous barrier via tight junctions (TJs). The development of a drug delivery system for use across the nasal muco...

Optimization of magnetophoretic-guided drug delivery to the olfactory region in a human nose model.

Magnetophoretic-guided delivery has been shown to be able to improve the olfactory doses. However, due to the complex nasal structure and quick decay of magnetic intensity, precise control of particle...

Development and Evaluation of a Novel Intranasal Spray for the Delivery of Amantadine.

The aim of this study was to develop and characterize an intranasal delivery system for amantadine hydrochloride (AMT). Optimal formulations consisted of a thermosensitive polymer Pluronic® 127 and e...

Nasal Mask Versus Nasal Prongs for Delivering Nasal Continuous Positive Airway Pressure in Preterm Infants with Respiratory Distress: A Randomized Controlled Trial.

To compare the effectiveness of nasal continuous positive airway pressure delivered by Nasal mask vs Nasal prongs with respect to continuous positive airway pressure failure.

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