Search Results for "Is Tramadol An Opioid"

16:10 EDT 23rd March 2017 | BioPortfolio

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Trends in Tramadol: Pharmacology, Metabolism, and Misuse

Learn about the unique characteristics of tramadol, its pharmacogenomic considerations, and its potential for abuse in this comprehensive review. Anesthesia & Analgesia

Loss of μ opioid receptor signaling in nociceptors, but not microglia, abrogates morphine tolerance without disrupting analgesia

μ opioid receptors (MORs) expressed on primary afferent nociceptor neurons are responsible for two maladaptive side-effects of chronic opioid use: opioid tolerance and opioid-induced hyperalgesia (pa...

Expanded Access to Opioid Treatment Offered

The U.S. Department of Health and Human Services (HHS) announced the expansion of access to opioid treatment in order to combat the opioid epidemic in the United States. HHS is growing access to medic...

Lifesaving App for Opioid Users

Opioid users and their friends and families may soon have an app to locate a source of naloxone, the antidote that can stop or reverse the effects of an opioid overdose.

Cures Act Releases $500 Million to States Hit by Opioid Epidemic

Hard-hit states will receive more funds to combat the opioid crisis as opioid-related deaths continue to surge.

Kennedy-Gingrich Anti-Opioid Group Funded By Maker Of Opioid Addiction Medication

Braeburn Pharmaceuticals, which won approval last year to market an implant that continuously dispenses the opioid addiction medicine buprenorphine, entered into an agreement to make a $900,000 charit...

The Multidisciplinary Approach To End The Opioid Epidemic

This month, Cigna Corp did away with pre-authorization requirements that had previously stood between those struggling with opioid addiction and treatment, an action that is just one of the many colla...

Insurer Curbs Opioid Prescriptions

As unintentional opioid overdose deaths skyrocketed 4 years ago in Massachusetts, a private insurer’s utilization review program apparently stemmed the tide of prescription opioid use among its memb...

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An Exploratory Study Evaluating The Impact Of Opioid And Non-Opioid Pain Medications On Serum/Plasma Free Testosterone And Free Estradiol Concentrations.

Chronic use of opioid medications has been reported to cause altered sexual function. It is not known if non-opioid pain medications have similar effects. Assessment of this effect through the measure...


Tramadol and tapentadol are centrally acting, synthetic opioid analgesics used in the treatment of moderate to severe pain. Main metabolic patterns for these drugs in humans are well characterized. Tr...

Cognitive Impairment and Tramadol Dependence.

Cognitive impairment is one of the consequences of substance abuse. Tramadol abuse is a public health problem in Egypt. The objective of this study was to estimate the prevalence and correlates of cog...

Bifunctional peptide-based opioid agonist/nociceptin antagonist ligand for dual treatment of nociceptive and neuropathic pain.

Drugs able to treat both nociceptive and neuropathic pain effectively without major side effects are lacking. We developed a bifunctional peptide-based hybrid (KGNOP1) that structurally combines a mu-...

Efficacy of the prophylactic administration of tramadol against postoperative shivering: a meta-analysis of randomized controlled trials.

Postoperative shivering (POS) is a common complication that occurs after regional and general anesthesia. Thus far, numerous studies have reported on the effectiveness of tramadol in preventing or tre...

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