Search Results for "Is Tramadol An Opioid"

09:26 EDT 31st July 2015 | BioPortfolio

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Design, synthesis and biological evaluation of N-phenylalkyl-substituted tramadol derivatives as novel μ opioid receptor ligands

ERs See Spike in Narcotic Painkiller Abuse Cases

THURSDAY, May 14, 2015 -- There was a sharp rise in the number of emergency room visits involving the narcotic painkiller tramadol between 2005 and 2011, two new government reports show. Tramadol is t...

Tramadol-related ER visits up 2005 to 2011

(HealthDay)—There was a sharp rise in the number of emergency department visits involving tramadol between 2005 and 2011, two new government reports show.

Preventing Prescription Opioid Abuse—Reply

In Reply We agree with Drs Ballantyne and Kolodny that opioid analgesics are not the most effective treatment option for certain types of chronic pain. This recognition, combined with the public healt...

Many opioid overdoses linked to lower prescribed doses, intermittent use

Overdoses of opioid pain medications frequently occur in people who aren't chronic users with high prescribed opioid doses—the groups targeted by current opioid prescribing guidelines, reports a stu...

Study highlights growing problem of opioid withdrawal in newborns

Prescribers should consider the risks of addiction and neonatal opioid withdrawal before starting opioid pain relief, particularly in women of childbearing age.

The Tramadol Wars

You may recall the report of the synthetic analgesic tramadol as a natural product from Cameroon, and the subsequent report that it was nothing of the kind. (That's the paper that brought the surprisi...

Significant blocking of opioid tolerance with mesenchymal stem cell transplant

Mesenchymal stem cell (MSC) transplantation reduced opioid tolerance and opioid-induced hyperalgesia caused by daily morphine injections in rats, according to new research. Not only was opioid toleran...

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Tramadol for postoperative pain treatment in children.

According to current recommendations a multimodal approach is believed to be the gold standard for postoperative pain treatment in children. However, several surveys in the last few years demonstrated...

The Pharmacogenetics of Tramadol.

Tramadol hydrochloride is used worldwide as an analgesic drug with a unique dual function. The metabolic enzymes cytochrome P450 (CYP) 3A4, CYP2B6, and CYP2D6 and the various transporters [adenosine t...

Effects of Tramadol on Substantia Gelatinosa Neurons in the Rat Spinal Cord: An In Vivo Patch-Clamp Analysis.

Tramadol is thought to modulate synaptic transmissions in the spinal dorsal horn mainly by activating µ-opioid receptors and by inhibiting the reuptake of monoamines in the CNS. However, the precise ...

Colon specific drug delivery of tramadol HCl for chronotherapeutics of arthritis.

The objective of present work is to develop and evaluate a matrix system for Chronotherapeutic delivery of centrally acting of opioid analgesic (tramadol HCl) to treat nocturnal symptoms of arthritis ...

Tramadol-related psychosis in a patient with bipolar I disorder.

Introduction Tramadol hydrochloride (HCl) is a centrally acting synthetic opioid analgesic. Psychotic symptoms are relatively rare in reported adverse events. Here, we report a patient who presented w...

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