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10:51 EDT 22nd July 2017 | BioPortfolio

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Clinical trial looks at tramadol for opioid withdrawal

A randomized clinical trial published by JAMA Psychiatry compared tramadol extended-release with clonidine and buprenorphine for the management of opioid withdrawal symptoms in patients with opioid us...

Tramadol May Offer a Better Option for Opioid Withdrawal

Extended-release formulations of the analgesic tramadol hydrochloride may provide an attractive alternative to two commonly used medications for opioid withdrawal. Medscape Medical News

Chronic pain patients say opioid crackdown is hurting them

Jim Watkins lives with pain so intense it can snatch his breath away. He has osteogenesis imperfecta, also known as brittle bone disease, and the best way he has found to control the anguish is with d...

FDA Drug Safety Communication: FDA restricts use of prescription codeine pain and cough medicines and tramadol pain medicines in children; recommends against use in breastfeeding women

FDA is restricting the use of codeine and tramadol medicines in children. Codeine is approved to treat pain and cough, and tramadol is approved to treat pain. These medicines carry serious risks, in...

FDA Issues Restriction, Warning About Codeine and Tramadol

NewsCodeine and tramadol medicines: drug safety communication—restricting use in children, recommending against use in breastfeeding women.

Codeine cough syrup should not be given to kids, FDA warns

The FDA issued its strongest level of drug warnings concerning children's usage of the opioid pain-relievers codeine and tramadol.

Codeine and Tramadol Can Cause Breathing Problems for Children

The FDA is strengthening drug labels for codeine and tramadol to protect children and nursing babies.

Don't Give Kids Medicines With Codeine, Tramadol: FDA

THURSDAY, April 20, 2017 -- Parents shouldn't give their children any medications containing the narcotics codeine or tramadol, because they can cause life-threatening breathing problems, the U.S. Foo...

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An Exploratory Study Evaluating The Impact Of Opioid And Non-Opioid Pain Medications On Serum/Plasma Free Testosterone And Free Estradiol Concentrations.

Chronic use of opioid medications has been reported to cause altered sexual function. It is not known if non-opioid pain medications have similar effects. Assessment of this effect through the measure...

Tramadol with or without paracetamol (acetaminophen) for cancer pain.

Tramadol is an opioid analgesic licensed for use in moderate to severe pain. It is considered as a low risk for abuse, so control regulations are not as stringent as for 'strong' opioids such as morph...

A disposition kinetic study of Tramadol in bile duct ligated rats in perfused rat liver model.

Tramadol hydrochloride is a centrally acting synthetic opioid analgesic drug and is used to treat chronic pain. In this study, the effects of Bile Duct Ligation (BDL) on the pharmacokinetics of tramad...

Efficacy of Tramadol Extended-Release for Opioid Withdrawal: A Randomized Clinical Trial.

Opioid use disorder (OUD) is a significant public health problem. Supervised withdrawal (ie, detoxification) from opioids using clonidine or buprenorphine hydrochloride is a widely used treatment.

The anti-inflammatory effect of tramadol in the temporomandibular joint of rats.

Tramadol is a centrally acting analgesic drug able to prevent nociceptor sensitization when administered into the temporomandibular joint (TMJ) of rats. The mechanism underlying the peripheral anti-in...

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