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Search Results for "Lawsuits Against Pilot Taking Atenolol"

14:27 EDT 18th April 2014 | BioPortfolio

Original Source: Atenolol exposure and risk for development of adverse metabolic effects: a pilot study.

Abstract Study Objective. To evaluate whether the level of systemic exposure to atenolol explains observed interindividual differences in adverse metabolic responses. Design. Open-label, prospective, pharmacokinetic pilot substudy of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study. Setting. General clinical research center. Patients. Fifteen hypertensive adults (mean age 46 +/- 8.9 yrs) who were enrolled in the PEAR study. Intervention. Patients received atenolol therapy for at lea...

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Prediction of in vivo atenolol removal by high-permeability hemodialysis based on an in vitro model.

Purpose. In order to update our data on drug dialyzability using the high-permeability dialysis membranes, atenolol elimination by an in vitro dialysis model was compared to that observed in six patie...

Formulation and evaluation of fixed-dose combination of bilayer gastroretentive matrix tablet containing atorvastatin as fast-release and atenolol as sustained-release.

The objective of the present study was to develop bilayer tablets of atorvastatin and atenolol that are characterized by initial fast-release of atorvastatin in the stomach and comply with the release...

Design, synthesis, and in vitro kinetics study of atenolol prodrugs for the use in aqueous formulations.

Based on DFT, MP2, and the density functional from Truhlar group (hybrid GGA: MPW1k) calculations for an acid-catalyzed hydrolysis of nine Kirby's N-alkylmaleamic acids and two atenolol prodrugs were...

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