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The US Food and Drug Administration (FDA) has issued a new warning to all drug labels for Eli Lilly’s antipsychotic drug, olanzapine. The drug can cause a rare but serious skin reaction, called DRES...
ArticleThe French drug maker expects to have this drug approved in the U.S. this August followed by a first-quarter approval in Europe next year.
The two most common drug-drug interactions involving statins are the ones mediated by the cytochrome P-450 enzyme system and permeability glycoprotein, the researchers write. Heartwire from Medscape
NewsDiabetes drug development is riskier compared to all drug development, according to the Tufts Center for the Study of Drug Development.
Drug discovery involves using assays to predict potential drug–drug interactions before clinical trials begin, but predicting clinical toxicity is complicated. This eBriefing examines in vivo, i...
By: Leonard Sacks, M.D., and Mili Duggal, Ph.D., M.P.H. Though many people do not know it, FDA does much more to facilitate drug approval than evaluate new drug applications. We are also actively invo...
MUMBAI (Reuters) - The U.S. Food and Drug Administration has pulled up a former Sun Pharmaceutical drug factory for "knowingly" releasing 27 lots of the hypertension drug clonidine last year, despite ...
In Reply We agree with Dr Schreuder and colleagues about the importance of the drug interaction between cyclosporine and itraconazole and the necessity of strict therapeutic drug monitoring of cyclosp...
Attentional bias for drug-related stimuli (Drug-AB) has been shown to play an important role in drug abuse, drug treatment, and relapse. This study sought to retrain Drug-AB using the Drug Attention C...
Most drug users initiate illicit drug use during adolescence and young adulthood. Although in the general population a trend towards a decrease in drug use can be seen, patterns of drug use among stud...
Moxifloxacin and rifampicin are all the first line options for treatment of active tuberculosis, which are often combined for the treatment of multi-drug resistance pulmonary tuberculosis in clinic. H...
The competition of two drugs for the same metabolizing enzyme is a common mechanism for drug-drug interactions that can lead to altered kinetics in drug metabolism and altered elimination rates in viv...
Drug-drug co-crystallization could realize combination drugs at a molecular level. Two polymorphic co-crystals between VD2 and VD3 were successfully designed and synthesized. These enantiotropic polym...