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22:56 EST 6th February 2016 | BioPortfolio

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Safety monitoring of drug interchangeability

When a brand-name drug is going off patent protection, pharmaceutical or generics companies may file an abbreviated new drug application (ANDA) for approval of a generic drug. As indicated by the US F...

In 2015, First-Of-A Kind Drug Approvals On The Rise

This trend reflected an industry-wide focus on drugs for rare and hard-to-treat diseases. Meanwhile, Gilead's hepatitis C combo drug gets a Food and Drug Administration priority review, a gene-editing...

A Solution for High Drug Prices: Drug Lists with Maximum Allowable Prices

Many drug prices, particularly those used to treat cancer, have risen to astronomic levels. Medicare is prohibited by law from negotiating with drug companies to achieve lower prices (see: Drug Compan...

ARV Drug Use and HIV Drug Resistance Among HIV+ Black MSM

This report examines ARV drug use and HIV drug resistance among HIV-infected men who have sex with men. JAIDS: Journal of Acquired Immune Deficiency Syndromes

Sanofi files NDA for type 2 diabetes drug with US FDA

French drug major Sanofi on Tuesday said the US Food and Drug Administration has accepted a New Drug…

US drug agency approves drug for low sexual desire in women

The US Food and Drug Administration (FDA) has approved the first drug for the treatment of women with low sexual desire. The drug, flibanserin, which is made by Sprout Pharmaceuticals, of Raleigh,... ...

FDA Upgrades Drug Shortage App

The U.S. Food and Drug Administration has launched the Drug Shortages 2 mobile application for Android devices. The upgrade will enable users to receive notifications when the Agency adds or updates s...

$80m Windfall Will Push 7 ADC Drug Candidates Into Clinic Within Two Years

By generating $80m through its latest equity placement, oncology drug development company ADC Therapeutics (ADCT) says it is now well-funded to advance its portfolio of linked tumor-targeted antibody ...

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Do drug seizures predict drug-related emergency department presentations or arrests for drug use and possession?

Direct evidence of the effect of drug seizures on drug use and drug-related harm is fairly sparse. The aim of this study was to see whether seizures of heroin, cocaine and ATS predict the number of pe...

Drugs and discretionary power in prisons: The officer's perspective.

Drugs play an increasing role in contemporary prison life. Prisoners' drug use, drug smuggling and drug selling have also had a growing impact on the work routines and practices of prison officers. Th...

Image-guided drug delivery: preclinical applications and clinical translation.

Image-guided drug delivery refers to the combination of drug targeting and imaging. Preclinically, image-guided drug delivery can be used for several different purposes, including for monitoring biodi...

Large-Scale Prediction of Beneficial Drug Combinations Using Drug Efficacy and Target Profiles.

The identification of beneficial drug combinations is a challenging issue in pharmaceutical and clinical research toward combinatorial drug therapy. In the present study, we developed a novel computat...

Drug-drug co-crystallization presents a new opportunity for the development of stable vitamins.

Drug-drug co-crystallization could realize combination drugs at a molecular level. Two polymorphic co-crystals between VD2 and VD3 were successfully designed and synthesized. These enantiotropic polym...

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