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16:07 EDT 23rd September 2017 | BioPortfolio

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FDA Approves First New ALS Drug in More than 20 Years

NewsThe Food and Drug Administration has approved the drug Radicava, also known as edaravone, for the treatment for amyotrophic lateral sclerosis (ALS). This is the first time an ALS drug has been cl...

FDA Asks Drug Company to Pull Painkiller in First

The U.S. Food and Drug Administration (FDA) announced today (June 8) that it has requested that Endo Pharmaceuticals, a drug company, remove the opioid painkiller Opana ER from the drug market. This ...

At $475,000, new cancer drug raises thorny questions about drug pricing — and value

Pricing for the Novartis drug, which treats an aggressive form of childhood leukemia, has stirred the heated national debate over prescription drug costs.

New Method Yields Shortcut in Drug Development

NewsThe majority of promising new drug candidates are effective only within the body’s cells, but quick general methods of determining intracellular drug quantities are lacking.

France to prosecute its drug regulator and Servier in scandal over diabetes drug

France’s drug regulator and one of its leading drug companies, Servier, will stand trial as legal persons over the marketing of the antidiabetes and weight loss drug benfluorex (marketed in France a...

Drug Development at the Portfolio Level

This Viewpoint discusses the drug development portfolio—a family of trials assessing a drug for different indications or in different combinations with other drugs—and summarizes some of the chall...

Documents shed light on Trump’s Drug Pricing and Innovation Working Group

To solve the crisis of high drug prices, the group discussed strengthening the monopoly rights of pharmaceuticals overseas, ending discounts for low-income hospitals and accelerating

FDA approves first new drug for ALS in decades

(HealthDay)—The first new drug to treat amyotrophic lateral sclerosis (ALS) in more than 20 years has been approved by the U.S. Food and Drug Administration.

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Identifying Drug-Drug Interactions by Data Mining: A Pilot Study of Warfarin-Associated Drug Interactions.

Knowledge about drug-drug interactions commonly arises from preclinical trials, from adverse drug reports, or based on knowledge of mechanisms of action. Our aim was to investigate whether drug-drug i...

Trends in reports of driving following illicit drug consumption among regular drug users in Australia, 2007-2013: Has random roadside drug testing had a deterrent effect?

Driving following illicit drug consumption ('drug-driving') is a potential road safety risk. Roadside drug testing (RDT) is conducted across Australia with the dual aims of prosecuting drivers with dr...

Drug use generations and patterns of injection drug use: Birth cohort differences among people who inject drugs in Los Angeles and San Francisco, California.

A robust literature documents generational trends in drug use. We examined the implications of changing national drug use patterns on drug injection histories of diverse people who inject drugs (PWID)...

Drug cue reactivity involves hierarchical instrumental learning: evidence from a biconditional Pavlovian to instrumental transfer task.

Drug cue reactivity plays a crucial role in addiction, yet the underlying mechanisms are poorly understood. According to the binary associative account, drug stimuli retrieve an expectation of the dru...

Managing Drug-Drug Interaction Between Ombitasvir, Paritaprevir/Ritonavir, Dasabuvir, and Mycophenolate Mofetil.

No drug-drug interaction study has been conducted to date for the combination of ombitasvir, paritaprevir/ritonavir, dasabuvir (3D), and mycophenolic acid (MPA). We here report the case of a hepatitis...

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