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03:33 EST 7th December 2016 | BioPortfolio

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FDA Approves Supplemental New Drug Application for Veltassa Removing Boxed Warning Regarding Drug-Drug Interactions

REDWOOD CITY, Calif., November 27, 2016 – Relypsa, Inc., a Vifor Pharma company, today announced that the U.S. Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sN...

Sanofi's Diabetes Drug Hits Phase 3 Study Targets

ArticleThe French drug maker expects to have this drug approved in the U.S. this August followed by a first-quarter approval in Europe next year.

Statin Drug-Drug Interactions in CV Patients Underappreciated

The two most common drug-drug interactions involving statins are the ones mediated by the cytochrome P-450 enzyme system and permeability glycoprotein, the researchers write. Heartwire from Medscape

Study: Diabetes Drug Development is Riskier Compared to All Drug Development

NewsDiabetes drug development is riskier compared to all drug development, according to the Tufts Center for the Study of Drug Development.

FDA warns former Sun Pharma U.S. drug factory over quality concerns

MUMBAI (Reuters) - The U.S. Food and Drug Administration has pulled up a former Sun Pharmaceutical drug factory for "knowingly" releasing 27 lots of the hypertension drug clonidine last year, despite ...

FDA’s Clinical Investigator Training Helps Support the Drug Development Process

By: Leonard Sacks, M.D., and Mili Duggal, Ph.D., M.P.H. Though many people do not know it, FDA does much more to facilitate drug approval than evaluate new drug applications. We are also actively invo...

New capsule achieves long-term drug delivery

(Massachusetts Institute of Technology) Researchers at MIT and Brigham and Women's Hospital have developed a drug capsule that remains in the stomach for up to two weeks after being swallowed, gradual...

Drug-Drug Interactions in Treatment Using Azole Antifungal Agents—Reply

In Reply We agree with Dr Schreuder and colleagues about the importance of the drug interaction between cyclosporine and itraconazole and the necessity of strict therapeutic drug monitoring of cyclosp...

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Effects of Attention Control Training on Drug Abusers' Attentional Bias and Treatment Outcome.

Attentional bias for drug-related stimuli (Drug-AB) has been shown to play an important role in drug abuse, drug treatment, and relapse. This study sought to retrain Drug-AB using the Drug Attention C...

Changes in Drug Use Among Belgian Higher Education Students: A Comparison Between 2005, 2009, and 2013.

Most drug users initiate illicit drug use during adolescence and young adulthood. Although in the general population a trend towards a decrease in drug use can be seen, patterns of drug use among stud...

Drug-drug interactions between moxifloxacin and rifampicin based on pharmacokinetics in vivo in rats.

Moxifloxacin and rifampicin are all the first line options for treatment of active tuberculosis, which are often combined for the treatment of multi-drug resistance pulmonary tuberculosis in clinic. H...

Measuring Drug Metabolism Kinetics and Drug-Drug Interactions with SAMDI Mass Spectrometry.

The competition of two drugs for the same metabolizing enzyme is a common mechanism for drug-drug interactions that can lead to altered kinetics in drug metabolism and altered elimination rates in viv...

Drug-drug co-crystallization presents a new opportunity for the development of stable vitamins.

Drug-drug co-crystallization could realize combination drugs at a molecular level. Two polymorphic co-crystals between VD2 and VD3 were successfully designed and synthesized. These enantiotropic polym...

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