Search Results for "Mdvp Drug"

22:11 EDT 21st September 2014 | BioPortfolio

Original Source: GHB and synthetic cathinones: clinical effects and potential consequences.

Designer drugs belong to a group of legally or illegally produced substances that are structurally and pharmacologically very similar to illicit drugs. In the past, designer drugs were often used during all-night dance parties, but they are now consumed in multiple settings from college bars to parks to private house parties. Most of these club drugs can be bought on legal websites and home-delivered for private parties. Recently, legal highs have once again become a burning media issue across the world. Ou...

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Gut Microbes and Medicines: How the GI environment impacts drug metabolism

A wide range of factors determines the safety and efficacy of a drug. For example, microorganisms in the gastrointestinal tract impact how a drug gets metabolized. Topics in this discussion includ...

EMA, FDA Grant Glioblastoma Drug Orphan Drug Designation

AbbVie announced the European Medicines Agency (EMA) and the U.S. Food and Drug Administration (FDA) have granted orphan drug designation to AbbVie's investigational compound ABT-414, an anti-epiderma...

Pakistan Drug Regulator Hits Back At Drug Makers Over Suits

Pakistan's drug regulatory agency has struck back at drug makers and importers by blaming them for causing the problems in their complaints by constantly dragging it into court over drug pricing issue...

Genomics-Enabled Drug Repositioning and Repurposing Insights From an IOM Roundtable Activity

Drug repositioning or drug repurposing (terms often used interchangeably) is the process whereby alternative uses or indications are identified for a drug. Repurposing can encompass the pursuit of nov...

Neurotrophic Keratitis Drug Gets Orphan Drug Designation

Dompe, a leader in R&D for new therapeutic solutions for the treatment of rare diseases, announced that rhNGF (Recombinant Human Nerve Growth Factor) has been designated as an orphan drug by the A...

US FDA calls for lower starting dose for sleep drug Lunesta

The US Food and Drug Administration says it has required the manufacturer of the sleep drug Lunesta (eszopiclone) to change the drug label and lower the current recommended starting dose. The drug is ...

FDA accepts first application for approval of a biosimilar drug, could decide in 10 months

The Food and Drug Administration is reviewing research data on what could become the first U.S.-approved "biosimilar" drug, a cheaper, sort-of generic version of a biologic drug.

Critical Outcome seeks FDA orphan drug status for ovarian cancer drug COTI-2

Canada-based bioinformatics and accelerated drug discovery firm Critical Outcome Technologies (COTI) has submitted an orphan drug application to the US Food and Drug Administration (FDA) for its lead ...

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Hair drug testing results and self-reported drug use among primary care patients with moderate-risk illicit drug use.

This study sought to examine the utility of hair testing as a research measure of drug use among individuals with moderate-risk drug use based on the internationally validated Alcohol, Smoking, and Su...

Machine learning-based prediction of drug-drug interactions by integrating drug phenotypic, therapeutic, chemical, and genomic properties.

Drug-drug interactions (DDIs) are an important consideration in both drug development and clinical application, especially for co-administered medications. While it is necessary to identify all possib...

Pharmacokinetics of Lacosamide and Omeprazole Coadministration in Healthy Volunteers: Results from a Phase I, Randomized, Crossover Trial.

The antiepileptic drug lacosamide has a low potential for drug-drug interactions, but is a substrate and moderate inhibitor of the cytochrome P450 (CYP) enzyme CYP2C19.

Drug-induced lupus: Including anti-tumour necrosis factor and interferon induced.

Drug-induced lupus erythematosus is defined as a syndrome with clinical and serological features similar to systemic lupus erythematosus that is temporally related to continuous drug exposure and whic...

Current status and future prospects of drug delivery systems.

This is an overview of the current drug delivery systems (DDS) starting with various routes of drug administration. Various drug formulations are then described as well as devices used for drug delive...

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