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Put in the time now to optimize protein solubility so you don’t have to suffer later! With this in mind, here are some considerations and tips for selecting the optimal conditions for recombinant pr...
Juniper Pharma Services will up its solubility enhancement capabilities through the addition of a new spray-dryer at its site in Nottingham, UK.
Read more about Spray Drying Capabilities Overcome Solubility IssuesComments
Biospectrum Glenmark's current portfolio consists of 114 products authorized for distribution in the US marketplace and...
Type: Original PaperPurposeExcipients are essential for solubility enhancing formulations. Hence it is important to understand how additives impact key solution properties, particularly when supersatu...
Capsugel’s customized solutions advance challenging compounds
Type: Original PaperPurposeThis study explored the impact of non-sink receptor conditions on the in vitro skin permeation test (IVPT) and sought to estimate equivalent sink condition IVPT data.Methods...
Nystatin A1 , a polyene macrolide antifungal antibiotic, in a slightly basic or acidic solution undergoes an intramolecular transformation, yielding a structural isomer, the translactonisation product...
The solubility parameter seems to be a useful tool for thermodynamic characterisation of different materials. The solubility parameter concept can be used to predict sufficient miscibility or solubili...
In recent years there has been a growing interest in formulating solid dispersions, which purposes mainly include solubility enhancement, sustained drug release and taste masking. The most notable pro...
Solubility is one of the fundamental protein properties. It is of great interest because of its relevance to protein expression. Reduced solubility and protein aggregation are also associated with man...
Here, our interest is in predicting solubility in general, and we focus particularly on predicting how the solubility of particular solutes is modulated by the solvent environment. Solubility in gener...