Search Results for "Solubility Of Nystatin"

14:36 EDT 6th October 2015 | BioPortfolio

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Low solubility concern is driving market for solubility enhancement excipients, finds report

Among advanced solubility enhancement technologies, the most important are solid dispersions and lipid solubilisation

Big firms dominate solubility sector but demand creating space for small players, says Kline & Co

BASF, Abitec and Gattefossé dominate the solubility excipients market but growing demand for tech to enhance API solubility is creating opportunities for smaller suppliers according to new research.

AAPS PharmSciTech: pH-Dependent Solubility and Dissolution Behavior of Carvedilol—Case Example of a Weakly Basic BCS Class II Drug

Type: Original PaperThe objective of this study was to investigate the pH-dependent solubility and dissolution of weakly basic Biopharmaceutical Classification Systems (BCS) class II drugs, characteri...

Pharmaceutical Research: Assessment of Age-Related Changes in Pediatric Gastrointestinal Solubility

Type: Original PaperPurposeCompound solubility serves as a surrogate indicator of oral biopharmaceutical performance. Between infancy and adulthood, marked compositional changes in gastrointestinal (G...

Echo's cannabis API delivery formulation could aid low solubility drugs

A drug delivery platform which increased the bioavailability of a cannabis-based drug candidate 30% could be used to boost solubility of other APIs, says Echo Pharmaceuticals.

Hovione upping spray drying capacity to support rise in low solubility drugs

A new unit will up Hovione’s spray drying capacity 20% as it predicts a surge in demand for such a service in overcoming drug solubility issues.

The Powder Room - Improving Drug Water Solubility

In collaboration with Ghent University, Laboratoria Smeets has developed a new granulating technology capable of significantly improving drug water solubility. Managing director Dr Jef Verplaetse expl...

In vitro prediction of drug solubility with fasted-state simulated intestinal fluid (FaSSIF) with cholesterol (FaSSIF-C)

Screening in simulated intestinal fluid could help predict the in vivo effects of bile cholesterol on drug solubility.

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Preparation and in vitro evaluation of Nystatin micro emulsion based gel.

Nystatin is a polyene antimycotic obtained from Streptomyces noursei used in the treatment of topical and transdermal fungal infection. Nystatin is nearly insoluble in water (

A new simulated plasma for assessing the solubility of mineral trioxide aggregate.

Solubility of mineral trioxide aggregate (MTA) is an important characteristic that affects other properties such as microleakage and biocompatibility. Distilled water (DW) has previously been used for...

Head-To-Head Comparison of Different Solubility-Enabling Formulations of Etoposide and Their Consequent Solubility-Permeability Interplay.

The purpose of this study was to conduct a head-to-head comparison of different solubility-enabling formulations, and their consequent solubility-permeability interplay. The low-solubility anticancer ...

Predicting the solubility advantage of amorphous pharmaceuticals - a novel thermodynamic approach.

To improve the solubility and bioavailability of poorly-soluble active pharmaceutical ingredients (APIs), the transformation of crystalline APIs into the amorphous state has often been shown to be adv...

Cocrystal transition points: Role of cocrystal solubility, drug solubility, and solubilizing agents.

In this manuscript we bring together concepts that are relevant to the solubilization and thermodynamic stability of cocrystals in the presence of drug solubilizing agents. Simple equations are derive...

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