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Search Results for "Solubility Of Nystatin"

22:18 EDT 26th May 2016 | BioPortfolio

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Non‐monotonic course of protein solubility in aqueous polymer‐salt solutions can be modeled using the sol‐mxDLVO model

Protein purification is often performed using cost‐intensive chromatographic steps. To discover economic alternatives (e.g., crystallization), knowledge on protein solubility as a function of temper...

Getting physical in drug discovery: a contemporary perspective on solubility and hydrophobicity

The physical properties of drug molecules are frequently identified as a shortcoming of drugs in development. This article, the most highly-downloaded of Q3 2010, proposes a novel approach to the pred...

New spray-dryer to handle 20kg batches, as Juniper responds to solubility demand

Juniper Pharma Services will up its solubility enhancement capabilities through the addition of a new spray-dryer at its site in Nottingham, UK.

Spray Drying Capabilities Overcome Solubility Issues

Read more about Spray Drying Capabilities Overcome Solubility IssuesComments

AAPS PharmSciTech: Use of Polyvinyl Alcohol as a Solubility-Enhancing Polymer for Poorly Water Soluble Drug Delivery (Part 1)

Type: Original PaperPolyvinyl alcohol (PVAL) has not been investigated in a binary formulation as a concentration-enhancing polymer owing to its high melting point/high viscosity and poor organic solu...

Pharmaceutical Research: Characterization of Supersaturated Danazol Solutions – Impact of Polymers on Solution Properties and Phase Transitions

Type: Original PaperPurposeExcipients are essential for solubility enhancing formulations. Hence it is important to understand how additives impact key solution properties, particularly when supersatu...

Solving Solubility Woes

Capsugel’s customized solutions advance challenging compounds

AAPS PharmSciTech: Fusion Method for Solubility and Dissolution Rate Enhancement of Ibuprofen Using Block Copolymer Poloxamer 407

Type: Original PaperAim of current research was to prepare ibuprofen-poloxamer 407 binary mixtures using fusion method and characterize them for their physicochemical and performance properties. Binar...

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Preparation and in vitro evaluation of Nystatin micro emulsion based gel.

Nystatin is a polyene antimycotic obtained from Streptomyces noursei used in the treatment of topical and transdermal fungal infection. Nystatin is nearly insoluble in water (

The solubility parameter for biomedical polymers-Application of inverse gas chromatography.

The solubility parameter seems to be a useful tool for thermodynamic characterisation of different materials. The solubility parameter concept can be used to predict sufficient miscibility or solubili...

Determination of Solubility Parameters of Ibuprofen and Ibuprofen Lysinate.

In recent years there has been a growing interest in formulating solid dispersions, which purposes mainly include solubility enhancement, sustained drug release and taste masking. The most notable pro...

PON-Sol: prediction of effects of amino acid substitutions on protein solubility.

Solubility is one of the fundamental protein properties. It is of great interest because of its relevance to protein expression. Reduced solubility and protein aggregation are also associated with man...

Using MD simulations to calculate how solvents modulate solubility.

Here, our interest is in predicting solubility in general, and we focus particularly on predicting how the solubility of particular solutes is modulated by the solvent environment. Solubility in gener...

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