Search Results for "Solubility Of Nystatin"

01:59 EST 29th November 2015 | BioPortfolio

Matching Channels


Matching News

AAPS PharmSciTech: pH-Dependent Solubility and Dissolution Behavior of Carvedilol—Case Example of a Weakly Basic BCS Class II Drug

Type: Original PaperThe objective of this study was to investigate the pH-dependent solubility and dissolution of weakly basic Biopharmaceutical Classification Systems (BCS) class II drugs, characteri...

Non‐monotonic course of protein solubility in aqueous polymer‐salt solutions can be modeled using the sol‐mxDLVO model

Protein purification is often performed using cost‐intensive chromatographic steps. To discover economic alternatives (e.g., crystallization), knowledge on protein solubility as a function of temper...

Pharmaceutical Research: Assessment of Age-Related Changes in Pediatric Gastrointestinal Solubility

Type: Original PaperPurposeCompound solubility serves as a surrogate indicator of oral biopharmaceutical performance. Between infancy and adulthood, marked compositional changes in gastrointestinal (G...

Echo's cannabis API delivery formulation could aid low solubility drugs

A drug delivery platform which increased the bioavailability of a cannabis-based drug candidate 30% could be used to boost solubility of other APIs, says Echo Pharmaceuticals.

Hovione upping spray drying capacity to support rise in low solubility drugs

A new unit will up Hovione’s spray drying capacity 20% as it predicts a surge in demand for such a service in overcoming drug solubility issues.

The Powder Room - Improving Drug Water Solubility

In collaboration with Ghent University, Laboratoria Smeets has developed a new granulating technology capable of significantly improving drug water solubility. Managing director Dr Jef Verplaetse expl...

Overexpression of AtVIT1 Increases Accumulation of Iron in Cassava

Iron uptake in plants is limited due to its low solubility in neutral or alkaline soils. This is why plants rely on rhizosphere acidification to increase iron solubility. AtVIT1 gene from Arabidopsis ...

In vitro prediction of drug solubility with fasted-state simulated intestinal fluid (FaSSIF) with cholesterol (FaSSIF-C)

Screening in simulated intestinal fluid could help predict the in vivo effects of bile cholesterol on drug solubility.

Matching PubMed Articles

Preparation and in vitro evaluation of Nystatin micro emulsion based gel.

Nystatin is a polyene antimycotic obtained from Streptomyces noursei used in the treatment of topical and transdermal fungal infection. Nystatin is nearly insoluble in water (

Head-To-Head Comparison of Different Solubility-Enabling Formulations of Etoposide and Their Consequent Solubility-Permeability Interplay.

The purpose of this study was to conduct a head-to-head comparison of different solubility-enabling formulations, and their consequent solubility-permeability interplay. The low-solubility anticancer ...

Predicting the solubility advantage of amorphous pharmaceuticals - a novel thermodynamic approach.

To improve the solubility and bioavailability of poorly-soluble active pharmaceutical ingredients (APIs), the transformation of crystalline APIs into the amorphous state has often been shown to be adv...

Cocrystal transition points: Role of cocrystal solubility, drug solubility, and solubilizing agents.

In this manuscript we bring together concepts that are relevant to the solubilization and thermodynamic stability of cocrystals in the presence of drug solubilizing agents. Simple equations are derive...

The impact of structural modification of 1,2,4-thiadiazole derivatives on thermodynamics of solubility and hydration processes.

The influence of a structural modification on thermodynamic aspects of solubility and hydration processes of 1,2,4-thiadiazole drug-like compounds was investigated. A substitution in the phenyl ring o...

Search Whole site using Google


Advertisement Advertisement