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06:29 EDT 28th July 2016 | BioPortfolio

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Vitamin E

Naturally occurring vitamin E exists in eight chemical forms (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol) that have varying levels of biological act...

Follicle stimulating hormone FSH

Follicle-stimulating hormone (FSH) now has become an established means of ovulation induction (OI) as part of assisted reproductive technology (ART). FSH is used to induce development of multiple foll...

Oxford

Located in south-east England, Oxford is home to a world-famous academic institution, Oxford University, but is addition to this it hosts over 100 high-quality biotechnology companies with in 10 mil...

Herpes simplex virus HSV 1 HSV 2 HHV 1 HHV 2

Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family that infect humans. HSV-1 and HSV-2 cause the vira...

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The AAPS Journal: Metabolic Profile of 3-Acetyl-11-Keto-β-Boswellic Acid and 11-Keto-β-Boswellic Acid in Human Preparations In Vitro, Species Differences, and Bioactivity Variation

Type: Original Paper3-Acetyl-11-keto-β-boswellic acid (AKBA) and 11-keto-β-boswellic acid (KBA) are widely used in the clinic as anti-inflammatory drugs. However, these drugs have the poor bioavaila...

Combinatorial metabolic engineering of industrial Gluconobacter oxydans DSM2343 for boosting 5-keto-D-gluconic acid accumulation

L-(+)-tartaric acid (L-TA) is an important organic acid, which is produced from the cream of tartar or stereospecific hydrolysis of the cis-epoxysuccinate. The former method is limited by the availabi...

Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy

Abiraterone blocks androgen synthesis and prolongs survival in patients with castration-resistant prostate cancer, which is otherwise driven by intratumoral androgen synthesis. Abiraterone is metaboli...

Hey Drivers: Hands-Free Cellphones Not Risk-Free

WEDNESDAY, June 8, 2016 -- Talking on a hands-free phone while driving may be just as distracting and dangerous as using a hand-held phone, according to a new study. In lab-based tests, British resear...

The gluten-free diet in children: Do the risks outweigh the benefits?

The prevalence of celiac disease (CD), an autoimmune disease, is increasing. The only treatment for CD is a gluten-free diet. However, the increasing prevalence of CD does not account for the dispropo...

Cambrooke Therapeutics Launches KetoVie.com to Focus on Improving the Lives of Children with Epilepsy

Cambrooke Therapeutics Inc., an innovation leader in therapeutic nutrition for inborn errors of metabolism and now ketogenic diet therapy, announces the launch of their new KetoVi...

Snyder's of Hanover goes peanut-free

Gina AcostaJust in time for back to school, Snyder's of Hanover has transitioned its main pretzel bakery to a peanut-free production facility to accommodate consumer demand for snacks free of the ...

When it comes to knowing your true self, believe in free will

Diminishing a person's belief in free will leads to them feeling less like their true selves, according to recent research published in Social Psychological and Personality Science. In a pair of studi...

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Catalyst-Free Singlet Oxygen-Promoted Decarboxylative Amidation of α-Keto Acids with Free Amines.

A novel catalyst-free decarboxylative amidation of α-keto acids with amines under mild conditions has been developed. Advantages of the new protocol include avoidance of metal catalysts and high leve...

Asymmetric synthesis of aromatic β-amino acids using ω-transaminase: Optimizing the lipase concentration to obtain thermodynamically unstable β-keto acids.

Synthesized aromatic β-amino acids have recently attracted considerable attention for their application as precursors in many pharmacologically relevant compounds. Previous studies on asymmetric synt...

Catalyst-Free Insertion of Sulfoxonium Ylides into Aryl Thiols. A Direct Preparation of β-Keto Thioethers.

Insertion of sulfoxonium ylides into the S-H bond of aryl thiols without the need for a catalyst is demonstrated, furnishing β-keto thioethers in excellent yield in most cases. The method overcomes t...

Characterization and biological properties of copper(II)-ketoprofen complexes.

From the reaction of Cu(II) with the non-steroidal anti-inflammatory drug ketoprofen (Hketo), complex [Cu2(keto)4(H2O)2] was isolated, while the presence of a N,N'-donor heterocyclic ligand 2,2'-bipyr...

Merging Visible-Light Photocatalysis and Palladium Catalysis for C-H Acylation of Azobenzenes and Azoxybenzenes with alpha-Keto Acids.

An efficient C-H acylation of azobenzenes and azoxybenzenes with alpha-keto acids has been developed by combining palladium catalysis and visible-light photoredox catalysis at room temperature under 1...

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