Search Results for "Biochemistry Leukemia"

14:58 EDT 2nd September 2015 | BioPortfolio

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Chronic Leukemia

Chronic leukemia is a long term increase of abnormal white blood cells. It can be classed as myelogenous or lymphocytic leukemia. For more information see the Leukemia pages Add the Leukemia New...

Acute Leukemia

Acute leukemia occurs when a hematopoietic stem cell undergoes malignant transformation into a primitive, undifferentiated cell with abnormal longevity. These lymphocytes (acute lymphocytic leukemia...

Acute Myelocytic Leukemia AML

Acute myelocytic leukemia is a life-threatening disease in which the neutrophil, basophil, eosinophil, and monocyte precursors become cancerous and rapidly replace normal cells in the bone marrow. ...

Chronic Myelocytic Leukemia CML

Chronic myelocytic leukemia is the resulting disease when neutrophil, basophil, eosinophil, and monocyte progenitors become cancerous. It is usually caused by the presence of the Philadelphia chromo...

Acute Lymphocytic Leukemia ALL

Acute lymphocytic leukemia (ALL) is a life-threatening disease in which the cells that normally develop into lymphocytes become cancerous and rapidly replace normal cells in the bone marrow. ALL acc...

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Paucity of Somatic Mutations in Aggressive Childhood Leukemia

In-depth DNA sequencing and RNA expression analysis shows that a particularly aggressive form of infant and childhood leukemia--mixed-lineage leukemia-rearranged gene (MLL-R) acute lymphoblastic leuke...

Researchers effectively, safely overcome radiation resistance in leukemia with an engineered precision medicine

Improved survival rates have been demonstrated in mouse models of aggressive human leukemia using leukemia cells taken directly from patients, according to a new study.

Promising drug a 'new paradigm' for treating leukemia

Researchers at the University of Virginia School of Medicine have developed a compound that delays leukemia in mice and effectively kills leukemia cells in human tissue samples, raising hopes that the...

Basis for new treatment options for a fatal leukemia in children revealed

(MC Services AG) Acute lymphoblastic leukemia is the most common type of cancer in children. It can occur in various forms, differing not only by specific changes in the genetic material of the leukem...

Leukemia like Achilles, has its own weakness

Leukemia cells from patients suffering from chronic myeloid leukemia, especially in the advanced stage, lack one of the proteins: the famous BRCA1. Importantly, the protein is not present even if the ...

Promising drug for childhood acute leukemia: Where to next?

A recently-developed drug, already used safely in adult leukemia clinical trials, holds great promise for some children with an aggressive form of cancer known as acute lymphoblastic leukemia, a new s...

New treatment options for a fatal leukemia

In industrialized countries like in Europe, acute lymphoblastic leukemia is the most common form of cancer in children. An international research consortium lead by pediatric oncologists from the Univ...

Minimal residual disease alone not predictive in T-cell leukemia

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. This disease includes two subtypes, B-cell and T-cell leukemia, depending upon the type of white blood cell where the leukemia o...

Matching PubMed Articles

Curcumin Potentiates the Anti-leukemia Effects of Imatinib by Downregulation of the AKT/mTOR Pathway and BCR/ABL Gene Expression in Ph+ Acute Lymphoblastic Leukemia.

Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) is triggered by BCR/ABL and SRC family tyrosine kinases. They interact with each other and subsequently activate downstream grow...

Congenital Acute Myeloid Leukemia with Unique Translocation t(11;19)(q23;p13.3).

Congenital leukemia is rarely encountered in clinical practice, even in tertiary children's hospitals. Leukemia may cause significant coagulopathy, putting the patient at risk of intracranial hemorrha...

Cytogenetic Variation of B-Lymphoblastic Leukemia With Intrachromosomal Amplification of Chromosome 21 (iAMP21): A Multi-Institutional Series Review.

B-lymphoblastic leukemia (B-ALL) with intrachromosomal amplification of chromosome 21 (iAMP21) is a relatively uncommon manifestation of acute leukemia and limited predominantly to the pediatric popul...

Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia.

Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by systemic intravascular activation of coagulation, leading to deposition of fibrin in the bloodstream. It may occur...

Analysis of KRAS and NRAS gene mutations in Arab Asian children with acute leukemia: High frequency of RAS mutations in acute lymphoblastic leukemia.

KRAS and NRAS gene mutations are frequently observed in childhood leukemia. The objective of this study was to determine the frequency of RAS mutations and the association between RAS mutations and ot...

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