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18:33 EDT 27th June 2017 | BioPortfolio

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FDA approves hypertension generic

Brian BerkJubilant Pharma’s olmesartan medoxomil Tablets 5mg/20mg, 5mg/40mg, 10mg/20mg and 10mg/40mg is the generic version of Daiichi Sankyo’s Azor. read more

Momenta says Pfizer will fix plant but reiterates that Glatopa 40mg ANDA delay likely

Momenta Pharmaceuticals has reiterated its belief that problems at a US Pfizer plant mean the FDA is unlikely to reach a decision on its 40mg version of Teva’s Copaxone before April.

Mylan wins court ruling for Copaxone 40mg/mL patents

Global generic and specialist pharmaceuticals company Mylan has won a US District Court Ruling with regards to its Copaxone 40mg/mL patents.

Payer Insights: MS [2016]: Bulletin 3 [Updated: 01052017] Prices from USD $1045

Topics covered in this update include: payers' approaches to the reimbursement of Ocrevus ocrelizumab; Roche/Biogen for relapsing remitting multiple sclerosis RRMS and primary progressive multiple scl...

Multiple Sclerosis Payer Insight: Update Bulletin [April 2017] [Updated: 01042017] Prices from USD $1045

Topics covered in this update include: payers' approaches to the reimbursement of Ocrevus ocrelizumab; Roche/Biogen for relapsing remitting multiple sclerosis RRMS and primary progressive multiple scl...

Osimertinib receives full approval in the EU

The European Commission (EC) has granted full marketing authorisation for osimertinib 40mg and 80mg once-daily tablets for the treatment of adult patients with locally-advanced or metastatic epiderm...

Teva MS drug under threat in US

A US court has hit Teva where it hurts, invalidating four US patents on its latest version of multiple sclerosis drug, Copaxone. Mylan wants to market a cheaper version of Teva’s three-times a week...

Copaxone 40mg Generic At-Risk Launch Anticipated As Soon As February

Teva is seeking injunction to block generic entry after court rules four patents on the three-times-a-week dosage are invalid; analysts...   

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AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249.

Aflatoxin B1 (AFB1) contamination in the food chain is a major cause of hepatocellular carcinoma (HCC). More than 60% of AFB1 related HCC carry p53 codon 249 mutations but the causal mechanism remains...

Rapid mixing with high-throughput in a semi-active semi-passive micromixer.

In this paper, we investigate a novel alternating current electrothermal (ACET) micromixer driven by a high efficiency ACET micropump. The micromixer consists of thin film asymmetric pairs of electrod...

Beyond feast and famine: Selecting a PHA accumulating photosynthetic mixed culture in a permanent feast regime.

Currently, the feast and famine (FF) regime is the most widely applied strategy to select for polyhydroxyalkanoate (PHA) accumulating organisms in PHA production systems with mixed microbial cultures....

Acute oral 18-methoxycoronaridine (18-MC) decreases both alcohol intake and IV nicotine self-administration in rats.

The ibogaine derivative 18-methoxycoronaridine (18-MC) has been found to decrease self-administration of morphine, nicotine and alcohol in rats after systemic injection. However oral dosing is the pre...

Methyl jasmonate attenuates memory dysfunction and decreases brain levels of biomarkers of neuroinflammation induced by lipopolysaccharide in mice.

Neuroinflammation plays a central role in the etiology and progression of Alzheimer's disease (AD), a neurodegenerative disorder, characterized by a gradual loss of memory functions. Thus, it has been...

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