Search Results for "En Vivo EVP6124 Alzheimer"

10:02 EST 2nd March 2015 | BioPortfolio

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Cytoplasmic Protein Tau

One of the main pillars of current drug discovery and development activities in the pharmaceutical industry for Alzheimer's disease is prevention of the accumulation of misfolded proteins, i.e. ...

Histone Deacetylase HDAC Inhibitors

Histone deacetylase (HDAC) inhibitors are emerging as a new class of potential anticancer agents for the treatment of solid and hematological malignancies. HDAC inhibition causes acetylated nuclear ...

Nerve growth factor NGF

Nerve growth factor (NGF) is the prototypical member of the family of neurotrophin growth factors that are involved in the growth and survival of nervous tissue. NGF and its receptors, the tyrosine-...

Interleukin 1 IL 1 Receptor IL 1R

Interleukin-1 (IL-1) beta is a proinflammatory cytokine driving joint inflammation as well as systemic signs of inflammation, such as fever and acute phase protein production. Current therapy targetin...

Selective monoamine oxidase type B MAOB inhibitors

The clinical benefit of monoamine oxidase type B (MAO-B) inhibitors is thought to arise from an ability of these medications to enhance the level of dopamine by decreasing the catabolism. Additional...

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Amyloid Formation May Link Alzheimer, Type 2 Diabetes

The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D...

In-vivo imaging of grey and white matter neuroinflammation in Alzheimer’s disease: a positron emission tomography study with a novel radioligand, [18F]-FEPPA

Failed Alzheimer’s test shows in which direction the research should continue

Disappointing results in clinical Alzheimer’s studies discourage doctors and scientists from continuing their research into ɣ-secretases and a possible treatment against Alzheimer’s disease. In C...

Amyloid Formation May Link Alzheimer's, Type 2 Diabetes

The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D...

Marijuana Compound May Slow, Halt Alzheimer’s

Extremely low levels of the compound in marijuana known as delta-9-tetrahydrocannabinol, or THC, may slow or halt the progression of Alzheimer’s disease, a recent study from neuroscientists at the U...

Toxic Tau Could be Key to Alzheimer’s Treatment

For years, Alzheimer’s researchers have targeted amyloid beta in attempts to halt the progression of the disease, without success. Now, they have their sights set on a second brain protein: tau

Carefusion Signs Exclusive Ventilator Distribution Agreement with Breas

CareFusion, a San Diego-based medical technology company, announced it has signed an exclusive distribution agreement for the U.S. with Breas Medical for their Vivo line of ventilation equipment. U...

Vivo raises $427.7M for eighth fund

Vivo Capital (formerly Vivo Ventures) raised $427.7 million for Vivo Capital Fund VIII, according to an SEC filing. The firm, which declined to comment on the news, invests primarily in late-stage dev...

Matching PubMed Articles

Phase 3 Trial of Flutemetamol Labeled With Radioactive Fluorine 18 Imaging and Neuritic Plaque Density.

In vivo imaging of brain β-amyloid, a hallmark of Alzheimer disease, may assist in the clinical assessment of suspected Alzheimer disease.

Conscious Knowledge and Decision Making Under Ambiguity in Mild Cognitive Impairment and Alzheimer Disease.

BP Variability and Cognitive Impairment: Vascular Risk Factors for Alzheimer Disease?

Simple method for evaluation of planum temporale pyramidal neurons shrinkage in postmortem tissue of Alzheimer disease patients.

We measured the length of the pyramidal neurons in the cortical layer III in four subregions of the planum temporale (transitions into superior temporal gyrus, Heschl's gyrus, insular cortex, and Sylv...

Alzheimer disease: An interactome of many diseases.

Alzheimer Disease (AD) is an outcome as well as source of many diseases. Alzheimer is linked with many other diseases like Diabetes type 2, cholesterolemia, hypertension and many more. But how each of...

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